Evidence map›Paper›PMID 30782408›Full record

ArticleDevelopmental cell2019

An ERK Phosphoproteome Expands Chemotactic Signaling in Dictyostelium.

Alan R Kimmel

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Alan R KimmelLaboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, The National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: alank@helix.nih.gov.
National Institutes of Health · US

Funding

SIGNALING PATHWAYS IN CONTROL OF GROWTH AND DEVELOPMENTZIADK075040 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI KIMMEL, ALAN R · 2009 to 2025
$23.9M
6 · The paper itself

Abstract

In this issue of Developmental Cell, Nichols et al. (2019) establish the MAP kinase ErkB as a critical component for chemotaxis signaling in Dictyostelium. Using phosphoproteomics, they identify a chemoattractant-dependent ErkB targeted core set of signal transduction proteins, which collectively suggest an added mechanistic pathway for chemotactic regulation.

Indexed as

DictyosteliumChemotactic FactorsChemotaxisCyclic AMPSignal TransductionChemotactic FactorsCyclic AMP

Identifiers

PMID30782408
OpenAlexW2917761772

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.