Evidence map›Paper›PMID 30782265›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2019

Pertactin-deficient

Alex-Mikael Barkoff, Jussi Mertsola, Denis Pierard, Tine Dalby, Silje Vermedal Hoegh, Sophie Guillot, Paola Stefanelli, Marjolein van Gent, Guy Berbers, Didrik Vestrheim and 6 more

Open access · diamondAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
8.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.

  1. Pertactin deficiency ofHuman vaccines & immunotherapeutics · 2024
    Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Laboratory diagnosis of pertussis: A survey on provincial public health laboratory methods.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2026
    Article
  8. Article
  9. Article
  10. CD4+ T-cell immunity toDiscover immunity · 2026
    Review
  11. Article
  12. Review
  13. Article
  14. Vaccine antigen-based genotyping ofMicrobiology spectrum · 2025
    Article
  15. Pertussis before, during and after Covid-19.EMBO molecular medicine · 2025
    Review
  16. Review
  17. Review
  18. Review
  19. Macrolide-resistantEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 12 institutions in 10 countries.

Alex-Mikael BarkoffInstitute of Biomedicine, Department of Microbiology, Virology and Immunology, University of Turku, Turku, Finland.
Jussi MertsolaDepartment of Pediatrics and Adolescent Medicine, Turku University Hospital, Turku, Finland.
Denis PierardDepartment of Microbiology, Universitair Ziekenhuis Brussel (UZ Brussel), Vrije Universiteit Brussel (VUB), Brussels, Belgium.
Tine DalbyStatens Serum Institut, Infectious Disease Preparedness - Bacteria, Parasites and Fungi, Copenhagen, Denmark.
Silje Vermedal HoeghDepartment of Clinical Microbiology, Odense, University Hospital, Odense, Denmark.
Sophie GuillotInstitut Pasteur, Centre National de Référence de la Coqueluche et autres Bordetelloses, Paris, France.
Paola StefanelliDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Marjolein van GentCentre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
Guy BerbersCentre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
Didrik VestrheimDepartment of Vaccine Preventable Diseases, Norwegian Institute of Public Health, Oslo, Norway.
Margrethe Greve-IsdahlDepartment of Vaccine Preventable Diseases, Norwegian Institute of Public Health, Oslo, Norway.
Lena WehlinDepartment of Microbiology, Public Health Agency of Sweden, Solna, Sweden.
Margaretha LjungmanDepartment of Microbiology, Public Health Agency of Sweden, Solna, Sweden.
Norman K FryRespiratory and Vaccine Preventable Bacteria Reference Unit, Public Health England - National Infection Service, London, United Kingdom.
Kevin MarkeyNational Institute for Biological Standards and Control, Potters Bar, United Kingdom.
Qiushui HeInstitute of Biomedicine, Department of Microbiology, Virology and Immunology, University of Turku, Turku, Finland.
National Institute for Public Health and the Environment · NLNorwegian Institute of Public Health · NOPublic Health Agency of Sweden · SEUniversity of Turku · FIInstitut Pasteur · FRIstituto Superiore di Sanità · ITNational Institute for Biological Standards and Control · GBOdense University Hospital · DKPublic Health England · GBStatens Serum Institut · DKTurku University Hospital · FIVrije Universiteit Brussel · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IntroductionPertussis outbreaks have occurred in several industrialised countries using acellular pertussis vaccines (ACVs) since the 1990s. High prevalence of pertactin (PRN)-deficient

Indexed as

Antigens, BacterialBacterial Outer Membrane ProteinsBordetella pertussisEnzyme-Linked Immunosorbent AssayEuropeHumansPertussis ToxinPertussis VaccineTime FactorsVaccines, AcellularVirulence Factors, BordetellaWhooping CoughAntigens, BacterialBacterial Outer Membrane ProteinspertactinPertussis ToxinPertussis VaccineVaccines, AcellularVirulence Factors, Bordetellaacellular vaccinepertactinpertussisvaccination, Europe

Identifiers

PMID30782265
PMCPMC6381657
OpenAlexW2913347265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.