ArticleBMC gastroenterology2019
What is the impact of metabolic syndrome and its components on reflux esophagitis? A cross-sectional study.
Article in BMC gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Risk factors and 26-years worldwide prevalence of endoscopic erosive esophagitis from 1997 to 2022: a meta-analysis.Scientific reports · 2023Pooled it
- Genetic Evidence of Association Between Gastroesophageal Reflux Disease and Hypertensive Disorders in Pregnancy.JGH open : an open access journal of gastroenterology and hepatology · 2025Article
- Impact of Metabolic Health and Its Changes on Erosive Esophagitis Remission: A Cohort Study.Journal of neurogastroenterology and motility · 2025Article
- Metabolic syndrome is associated with gastroesophageal reflux disease in a large Taiwanese population study.International journal of medical sciences · 2025Article
- Development and validation of a novel nomogram to predict worsening of gastroesophageal reflux symptoms after laparoscopic sleeve gastrectomy using Lasso-logistic regression.Scientific reports · 2024Article
- Sex difference in the associations among risk factors with gastroesophageal reflux disease in a large Taiwanese population study.BMC gastroenterology · 2024Article
- A single-center retrospective study on epidemiological and Traditional Chinese Medicine syndrome characteristics of 21010 patients with reflux/heartburn symptoms.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2023Article
- Increased risk of reflux esophagitis in non-obese individuals with nonalcoholic fatty liver disease: a cross-sectional study.Annals of medicine · 2023Article
- Triglyceride-glucose index is associated with gastroesophageal reflux disease and erosive reflux disease: a health checkup cohort study.Scientific reports · 2022Article
- Cough hypersensitivity in patients with metabolic syndrome: a clinical finding and its possible mechanisms.BMC pulmonary medicine · 2021Article
- Associations between Lifestyle Habits, Perceived Symptoms and Gastroesophageal Reflux Disease in Patients Seeking Health Check-Ups.International journal of environmental research and public health · 2021Article
- The association between metabolic syndrome and erosive esophagitis: A systematic review and meta-analysis.EXCLI journal · 2021Review
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundThe prevalence rate of reflux esophagitis (RE) in Asia, including Taiwan, has increased dramatically in recent years. However, few studies have discussed on its relationship with metabolic syndrome (MetS). This study aimed to evaluate the correlation between RE and MetS and its components.
methodsWe conducted a cross-sectional study during 2013 to 2014 in Taiwan. A total of 4895 subjects who completed upper gastrointestinal endoscopy at the Health Examination Center of Changhua Christian Hospital were enrolled. RE was defined according to the upper gastrointestinal endoscopic findings and MetS was defined according to the Taiwanese criteria. Univariate and multivariate logistic regression analyses were applied to calculate odds ratios and 95% confidence intervals for each variable to assess the associated features for RE. We analyzed the relationship between the number of MetS components and the severity of RE using the chi-square test for trend.
resultsThe prevalence rates of MetS and RE were respectively 28.5 and 59.6%. According to univariate logistic regression analysis, MetS was significantly associated with RE and remained a positive association in multivariate logistic regression analysis (adjusted OR
conclusionThis study suggests that MetS is significantly related to the presence and the severity of RE.
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