Evidence map›Paper›PMID 30781874›Full record

ArticleMolecules (Basel, Switzerland)2019

Microbial Asymmetric Functionalization of β-Cyclocitral-Derived Tetramethyl-Substituted γ-Lactone.

Marcelina Mazur, Witold Gładkowski, Aleksandra Pawlak, Bożena Obmińska-Mrukowicz, Gabriela Maciejewska, Czesław Wawrzeńczyk

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Marcelina MazurDepartment of Chemistry, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland. marcelina.mazur@upwr.edu.pl.ORCID 0000-0002-6192-5248
Witold GładkowskiDepartment of Chemistry, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland. glado@poczta.fm.
Aleksandra PawlakDepartment of Pharmacology and Toxicology, Wrocław University of Environmental and Life Sciences, Norwida 31, 50-375 Wrocław, Poland. aleksandra.pawlak@upwr.edu.pl.
Bożena Obmińska-MrukowiczDepartment of Pharmacology and Toxicology, Wrocław University of Environmental and Life Sciences, Norwida 31, 50-375 Wrocław, Poland. bozena.obminska-mrukowicz@upwr.edu.pl.
Gabriela MaciejewskaCentral Laboratory of the Instrumental Analysis, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland. gabriela.maciejewska@pwr.edu.pl.
Czesław WawrzeńczykDepartment of Chemistry, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland. czeslaw.wawrzenczyk@upwr.edu.pl.
Wrocław University of Environmental and Life Sciences · PLWrocław University of Science and Technology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Searching for the new anticancer compounds we prepared three new β-cyclocitral-derived hydroxyl-γ-lactones by microbial hydroxylation of tetramethyl-substituted bicyclic γ-lactone. The substrate was transformed by the enzymatic system of filamentous fungi. Three out of fifteen strains were selected as effective biocatalysts (

Indexed as

AldehydesAntineoplastic AgentsArmillariaCell Line, TumorCell ProliferationDiterpenesFusariumHumansHydroxylationHydroxyl RadicalLactonesNeoplasmsSubstrate SpecificityTrametesAldehydesAntineoplastic Agentsbeta-cyclocitralDiterpenesHydroxyl RadicalLactonesantiproliferative activityArmillaria melleaasymmetric hydroxylationFusarium culmorumTrametes versicolor

Identifiers

PMID30781874
PMCPMC6412764
OpenAlexW2912085871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.