Evidence map›Paper›PMID 30781850›Full record

ReviewPharmaceutics2019

Mesoporous Silica Nanomaterials: Versatile Nanocarriers for Cancer Theranostics and Drug and Gene Delivery.

Samuel Kesse, Kofi Oti Boakye-Yiadom, Belynda Owoya Ochete, Yaw Opoku-Damoah, Fahad Akhtar, Mensura Sied Filli, Muhammad Asim Farooq, Md Aquib, Bazezy Joelle Maviah Mily, Ghulam Murtaza and 1 more

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Nanotheranostics: A Cutting-edge Technology for Cancer Management.Current pharmaceutical biotechnology · 2025
    Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Recent Advances in Plant Nanoscience.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Review
  20. AntisenseInternational journal of nanomedicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Samuel KesseDepartment of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China. kessejnr@yahoo.com.ORCID 0000-0002-6510-325X
Kofi Oti Boakye-YiadomDepartment of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China. otiboakye1000@gmail.com.
Belynda Owoya OcheteSchool of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 211198, China. belyndaochete@yahoo.com.
Yaw Opoku-DamoahAustralian Institute for Bioengineering & Nanotechnology, The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia. yawdamoah@gmail.com.
Fahad AkhtarSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China. fahadakhtar121@outlook.com.ORCID 0000-0003-0548-0333
Mensura Sied FilliDepartment of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China. Biasfili@yahoo.com.
Muhammad Asim FarooqDepartment of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China. pharma1154@yahoo.com.
Md AquibDepartment of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China. mdaquib0007@yahoo.com.
Bazezy Joelle Maviah MilyDepartment of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China. mmaviah@yahoo.fr.
Ghulam MurtazaDepartment of Pharmacy, COMSATS University Islamabad, Lahore Campus 54600, Pakistan. gmdogar356@gmail.com.
Bo WangDepartment of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China. bowang@cpu.edu.cn.

Funding

Chinese Government Scholarship 2016288010
6 · The paper itself

Abstract

Mesoporous silica nanomaterials (MSNs) have made remarkable achievements and are being thought of by researchers as materials that can be used to effect great change in cancer therapies, gene delivery, and drug delivery because of their optically transparent properties, flexible size, functional surface, low toxicity profile, and very good drug loading competence. Mesoporous silica nanoparticles (MSNPs) show a very high loading capacity for therapeutic agents. It is well known that cancer is one of the most severe known medical conditions, characterized by cells that grow and spread rapidly. Thus, curtailing cancer is one of the greatest current challenges for scientists. Nanotechnology is an evolving field of study, encompassing medicine, engineering, and science, and it has evolved over the years with respect to cancer therapy. This review outlines the applications of mesoporous nanomaterials in the field of cancer theranostics, as well as drug and gene delivery. MSNs employed as therapeutic agents, as well as their importance and future prospects in the ensuing generation of cancer theranostics and drug and therapeutic gene delivery, are discussed herein. Thus, the use of mesoporous silica nanomaterials can be seen as using one stone to kill three birds.

Indexed as

cancer theranosticscancer therapydrug deliverygene therapymesoporous silica nanomaterialsstem cell

Identifiers

PMID30781850
PMCPMC6410079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.