Evidence map›Paper›PMID 30781804›Full record

ArticleInternational journal of molecular sciences2019

Cytotoxic Activity of the Histone Deacetylase 3-Selective Inhibitor Pojamide on MDA-MB-231 Triple-Negative Breast Cancer Cells.

Claudio Luparello, Dalia Maria Lucia Asaro, Ilenia Cruciata, Storm Hassell-Hart, Supojjanee Sansook, John Spencer, Fabio Caradonna

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  6. Review
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  9. Review
  10. Cancers · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Claudio LuparelloDipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche (STEBICEF), Università di Palermo, Viale delle Scienze, 90128 Palermo, Italy. claudio.luparello@unipa.it.ORCID 0000-0001-9821-5891
Dalia Maria Lucia AsaroDipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche (STEBICEF), Università di Palermo, Viale delle Scienze, 90128 Palermo, Italy. daliaasaro@libero.it.
Ilenia CruciataDipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche (STEBICEF), Università di Palermo, Viale delle Scienze, 90128 Palermo, Italy. ilenia.cruciata@unipa.it.
Storm Hassell-HartDepartment of Chemistry, School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QJ, UK. S.Hassell-Hart@sussex.ac.uk.ORCID 0000-0002-7659-7312
Supojjanee SansookDepartment of Chemistry, School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QJ, UK. sansook_s@yahoo.com.
John SpencerDepartment of Chemistry, School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QJ, UK. j.spencer@sussex.ac.uk.ORCID 0000-0001-5231-8836
Fabio CaradonnaDipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche (STEBICEF), Università di Palermo, Viale delle Scienze, 90128 Palermo, Italy. fabio.caradonna@unipa.it.ORCID 0000-0002-7659-7312
University of Palermo · ITUniversity of Sussex · GB

Funding

Engineering and Physical Sciences Research Council EP/P026990/1Royal Thai Government S.S.Università degli Studi di Palermo FFR 2018
6 · The paper itself

Abstract

We examined the effects of the ferrocene-based histone deacetylase-3 inhibitor Pojamide (

Indexed as

ApoptosisBiomarkers, TumorCell CycleCell DeathCell Line, TumorCell SurvivalFemaleHistone Deacetylase 3Histone Deacetylase InhibitorsHistone DeacetylasesHumansMatrix MetalloproteinasesReactive Oxygen SpeciesTriple Negative Breast NeoplasmsBiomarkers, TumorHistone Deacetylase 3Histone Deacetylase InhibitorsHistone DeacetylasesMatrix MetalloproteinasesReactive Oxygen Speciesapoptosisautophagybreast cancer cellscell cyclecell viabilityhistone deacetylase inhibitormitochondrial transmembrane potentialreactive oxygen species

Identifiers

PMID30781804
PMCPMC6412298
OpenAlexW2912779354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.