Evidence map›Paper›PMID 30781749›Full record

ArticleInternational journal of environmental research and public health2019

Age-Related Differences in miRNA Expression in Mexican-American Newborns and Children.

Karen Huen, Daneida Lizarraga, Katherine Kogut, Brenda Eskenazi, Nina Holland

Open access · goldAbstract readComparative Study
In one paragraph

Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Karen HuenChildren's Environmental Health Laboratory, Global Berkeley Campus, University of California, Berkeley, 1301 S. 46th Street, Bldg 112, Richmond, CA 94804, USA. khuen@berkeley.edu.
Daneida LizarragaChildren's Environmental Health Laboratory, Global Berkeley Campus, University of California, Berkeley, 1301 S. 46th Street, Bldg 112, Richmond, CA 94804, USA. daneida.lizarraga@gmail.com.
Katherine KogutCenter for Children's Environmental Health, School of Public Health, University of California, Berkeley, 1995 University Avenue Suite 265, Berkeley, CA 94720, USA. kkogut8@berkeley.edu.
Brenda EskenaziCenter for Children's Environmental Health, School of Public Health, University of California, Berkeley, 1995 University Avenue Suite 265, Berkeley, CA 94720, USA. eskenazi@berkeley.edu.
Nina HollandChildren's Environmental Health Laboratory, Global Berkeley Campus, University of California, Berkeley, 1301 S. 46th Street, Bldg 112, Richmond, CA 94804, USA. ninah@berkeley.edu.
University of California, Berkeley · USCenter for Environmental Health · US

Funding

Project C: Epigenetic Effects of DDT/E and PBDEs on PubertyP01ES009605 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI ESKENAZI, BRENDA · 1999 to 2015
$11.2M
Maintaining and Expanding the CHAMACOS Epidemiology Cohort Infrastructure for Future GenerationsR24ES028529 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Robert Gunier · 2017 to 2026
$2.0M
PON Epigenetics and Neurodevelopment in ChildrenR01ES023067 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI HOLLAND, NINA T · 2014 to 2017
$1.3M
NIEHS NIH HHS P01 ES009605NIEHS NIH HHS R01 ES023067NIEHS NIH HHS R24 ES028529
6 · The paper itself

Abstract

Epigenetic mechanisms have emerged as an important pathway through which environmental exposures can affect health through the regulation of gene expression without changes in DNA sequence: microRNAs (miRNAs) are short non-coding RNAs that target protein-coding mRNAs, leading to post-transcriptional repression. They are involved in important physiologic processes, but little is known about how miRNA expression may change with age in children. We used an nCounter miRNA assay to assess the expression of 43 miRNAs in buffy coat samples collected from newborns (

Indexed as

Gene Expression Regulation, DevelopmentalAge FactorsChildGene Expression ProfilingHumansInfant, NewbornMexican AmericansMicroRNAsMicroRNAsagebloodmiRNA

Identifiers

PMID30781749
PMCPMC6406617
OpenAlexW2911916451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.