Evidence map›Paper›PMID 30781702›Full record

ArticleNanomaterials (Basel, Switzerland)2019

Elaboration of Trans-Resveratrol Derivative-Loaded Superparamagnetic Iron Oxide Nanoparticles for Glioma Treatment.

Fadoua Sallem, Rihab Haji, Dominique Vervandier-Fasseur, Thomas Nury, Lionel Maurizi, Julien Boudon, Gérard Lizard, Nadine Millot

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Nanoscale Drug Delivery Systems in Glioblastoma.Nanoscale research letters · 2022
    Review
  7. Review
  8. Review
  9. Functionalisation of FeIET nanobiotechnology · 2020
    Article
  10. Magnetic iron oxide nanoparticles for imaging, targeting and treatment of primary and metastatic tumors of the brain.Journal of controlled release : official journal of the Controlled Release Society · 2020
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Fadoua SallemLaboratoire Interdisciplinaire Carnot de Bourgogne (ICB), UMR 6303 CNRS/Université Bourgogne Franche-Comté, 21000 Dijon, France. fadouasallem@gmail.com.
Rihab HajiInstitut de Chimie Moléculaire de l'Université de Bourgogne (ICMUB), UMR 6302 CNRS/Université Bourgogne Franche-Comté, 21000 Dijon, France. hajirihab22@yahoo.com.
Dominique Vervandier-FasseurInstitut de Chimie Moléculaire de l'Université de Bourgogne (ICMUB), UMR 6302 CNRS/Université Bourgogne Franche-Comté, 21000 Dijon, France. dominique.vervandier-fasseur@u-bourgogne.fr.ORCID 0000-0002-2998-5873
Thomas NuryLaboratoire Bio-PeroxIL, EA7270, Université de Bourgogne Franche-Comté/Inserm, 21000 Dijon, France. thomas.nury@u-bourgogne.fr.
Lionel MauriziLaboratoire Interdisciplinaire Carnot de Bourgogne (ICB), UMR 6303 CNRS/Université Bourgogne Franche-Comté, 21000 Dijon, France. lionelmaurizi@gmail.com.ORCID 0000-0002-6346-7623
Julien BoudonLaboratoire Interdisciplinaire Carnot de Bourgogne (ICB), UMR 6303 CNRS/Université Bourgogne Franche-Comté, 21000 Dijon, France. julien.boudon@u-bourgogne.fr.ORCID 0000-0002-2500-5030
Gérard LizardLaboratoire Bio-PeroxIL, EA7270, Université de Bourgogne Franche-Comté/Inserm, 21000 Dijon, France. gerard.lizard@u-bourgogne.fr.ORCID 0000-0001-6330-0172
Nadine MillotLaboratoire Interdisciplinaire Carnot de Bourgogne (ICB), UMR 6303 CNRS/Université Bourgogne Franche-Comté, 21000 Dijon, France. nadine.millot@u-bourgogne.fr.ORCID 0000-0002-0127-3858
Centre National de la Recherche Scientifique · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, new nanohybrids based on superparamagnetic iron oxide nanoparticles (SPIONs) were elaborated and discussed for the first time as nanovectors of a derivative molecule of trans-resveratrol (RSV), a natural antioxidant molecule, which can be useful for brain disease treatment. The derivative molecule was chemically synthesized (4'-hydroxy-4-(3-aminopropoxy) trans-stilbene: HAPtS) and then grafted onto SPIONs surface using an organosilane coupling agent, which is 3-chloropropyltriethoxysilane (CPTES) and based on nucleophilic substitution reactions. The amount of HAPtS loaded onto SPIONs surface was estimated by thermogravimetric analysis (TGA) and X-ray photoelectron spectroscopy (XPS) analyses at 116 µmol·g

Indexed as

drug deliverygliomairon oxide superparamagnetic nanoparticlestrans-resveratrol derivative

Identifiers

PMID30781702
PMCPMC6409721
OpenAlexW2911433996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.