Evidence map›Paper›PMID 30781652›Full record

ArticlePathogens (Basel, Switzerland)2019

Maternal and Congenital Toxoplasmosis: Diagnosis and Treatment Recommendations of a French Multidisciplinary Working Group.

François Peyron, Coralie L'ollivier, Laurent Mandelbrot, Martine Wallon, Renaud Piarroux, François Kieffer, Eve Hadjadj, Luc Paris, Patricia Garcia-Meric

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 1 pooled it
16.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 1 synthesis or guideline pooled it, 217 citations in OpenAlex.

  1. Pooled it
  2. Review
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  7. Article
  8. Observational
  9. Review
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  12. Article
  13. Adherence to the Colombian guideline on congenital toxoplasmosisBiomedica : revista del Instituto Nacional de Salud · 2025
    Article
  14. Article
  15. Routine antenatal toxoplasmosis screening, is it necessary?Turkish journal of obstetrics and gynecology · 2025
    Article
  16. Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

François PeyronCivil hospices of Lyon. Department of Parasitology and Mycology, Croix Rousse Hospital, 69317 Lyon, France. francois.peyron@chu-lyon.fr.
Coralie L'ollivierAssistance Publique-Hôpitaux de Marseille, Department of Parasitology, Timone Hospital, 13005 Marseille, France. Coralie.LOLLIVIER@ap-hm.fr.ORCID 0000-0002-1086-3745
Laurent MandelbrotAssistance Publique-Hôpitaux de Paris, Department of Obstetrics and Gynecology, Louis Mourier Hospital, Colombes, Université Paris-Diderot, Paris, Inserm UMR1137 IAME: Infection, 75013 Paris, France. laurent.mandelbrot@aphp.fr.
Martine WallonCivil hospices of Lyon. Department of Parasitology and Mycology, Croix Rousse Hospital, 69317 Lyon, France. martine.wallon@chu-lyon.fr.
Renaud PiarrouxSorbonne Université, INSERM, Institut Pierre-Louis d'Epidémiologie et de Santé Publique, AP-HP, Hôpital Pitié-Salpêtrière, 75651 Paris, France. renaud.piarroux@aphp.fr.
François KiefferAssistance Publique-Hôpitaux de Paris, Department of Neonatology, Trousseau Hospital, 75012 Paris, France. francois.kieffer@aphp.fr.
Eve HadjadjAssistance Publique-Hôpitaux de Marseille, Ophtalmology Consultations, Sainte Marguerite Hospital, 13274 Marseille, France. Eve.HADJADJ@ap-hm.fr.
Luc ParisAssistance Publique-Hôpitaux de Paris, Department of Parasitology-Mycology, Pitié-Salpêtrière/Charles Foix University Hospital, 75651 Paris, France. luc.paris@aphp.fr.ORCID 0000-0003-3433-9603
Patricia Garcia-MericAssistance Publique-Hôpitaux de Marseille, Department of Neonatal Medicine; Hospital of the Conception, 13005 Marseille, France. Patricia.GARCIA@ap-hm.fr.
Assistance Publique Hôpitaux de Marseille · FRHospices Civils de Lyon · FRInserm · FRAssistance Publique – Hôpitaux de Paris · FRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Women infected with toxoplasmosis during pregnancy do not present symptoms in most cases, but the consequences of the congenital infection may be severe for the unborn child. Fetal damage can range from asymptomatic to severe neurological alterations to retinal lesions prone to potential flare up and relapses lifelong. Despite the possible severity of outcome, congenital toxoplasmosis (CT) is a neglected disease. There is no consensus regarding screening during pregnancy, prenatal/postnatal treatment or short or medium term follow-up. Since 1992, France has offered systematic serological testing to non-immune pregnant women, monthly until delivery. Any maternal infection is thus detected; moreover, diagnosis of congenital infection can be made at birth and follow-up can be provided. "Guidelines" drawn up by a multidisciplinary group are presented here, concerning treatment, before and after birth. The recommendations are based on the regular analysis of the literature and the results of the working group. The evaluation of the recommendations takes into account the robustness of the recommendation and the quality of the evidence.

Indexed as

congenital toxoplasmosisfollow-up of congenital infectionguidelinestreatment of fetal infections

Identifiers

PMID30781652
PMCPMC6470622
OpenAlexW2915220010

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.