Evidence map›Paper›PMID 30781636›Full record

ArticleInternational journal of environmental research and public health2019

Sub-lethal Doses of Polybrominated Diphenyl Ethers, in Vitro, Promote Oxidative Stress and Modulate Molecular Markers Related to Cell Cycle, Antioxidant Balance and Cellular Energy Management.

Simona Manuguerra, Cristóbal Espinosa Ruiz, Andrea Santulli, Concetta Maria Messina

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Mechanisms of Male Reproductive Toxicity of Polybrominated Diphenyl Ethers.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Simona ManuguerraDepartment of Earth and Sea Science, Laboratory of Marine Biochemistry and Ecotoxicology, University of Palermo, Via Barlotta 4, 91100 Trapani, Italy. simona.manuguerra@unipa.it.ORCID 0000-0002-9542-2833
Cristóbal Espinosa RuizDepartment of Earth and Sea Science, Laboratory of Marine Biochemistry and Ecotoxicology, University of Palermo, Via Barlotta 4, 91100 Trapani, Italy. cristobal.espinosaruiz@unipa.it.ORCID 0000-0002-3063-1634
Andrea SantulliDepartment of Earth and Sea Science, Laboratory of Marine Biochemistry and Ecotoxicology, University of Palermo, Via Barlotta 4, 91100 Trapani, Italy. andrea.santulli@unipa.it.ORCID 0000-0001-8089-5470
Concetta Maria MessinaDepartment of Earth and Sea Science, Laboratory of Marine Biochemistry and Ecotoxicology, University of Palermo, Via Barlotta 4, 91100 Trapani, Italy. concetta.messina@unipa.it.ORCID 0000-0003-3190-9420
University of Palermo · IT

Funding

progetto Centro Internazionale di Studi Avanzati su Ambiente, ecosistema e Salute umana - CISAS', funded by CIPE -MIUR- CUP B62F15001070005
6 · The paper itself

Abstract

In the present study, we evaluated the effects of different concentrations of the polybrominated diphenyl ethers (PBDEs) BDE-209, BDE-47 and BDE-99, on the vitality and oxidative stress of a HS-68 human cell culture exposed to the compounds for three days. The results showed that for this exposure time, only the highest concentrations produced a significant vitality reduction and oxidative stress induction (

Indexed as

AntioxidantsBiomarkersCell CycleCell LineEnergy MetabolismEnvironmental PollutantsFibroblastsHalogenated Diphenyl EthersHumansOxidative Stress2,2',4,4',5-brominated diphenyl ether2,2',4,4'-tetrabromodiphenyl etherAntioxidantsBiomarkersdecabromobiphenyl etherEnvironmental PollutantsHalogenated Diphenyl Ethersbiomarkersmetabolismoxidative stressPBDEsproliferation

Identifiers

PMID30781636
PMCPMC6406823
OpenAlexW2914321491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.