Evidence map›Paper›PMID 30781621›Full record

ArticleMolecules (Basel, Switzerland)2019

Ingredients in Zijuan Pu'er Tea Extract Alleviate β-Amyloid Peptide Toxicity in a

Fangzhou Du, Lin Zhou, Yan Jiao, Shuju Bai, Lu Wang, Junfeng Ma, Xueqi Fu

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Fangzhou DuNational Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun 130012, China. du_fangzhou@163.com.
Lin ZhouNational Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun 130012, China. 18744021315@163.com.
Yan JiaoNational Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun 130012, China. jiaoyan@novogene.com.
Shuju BaiNational Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun 130012, China. baisj16@mails.jlu.edu.cn.
Lu WangNational Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun 130012, China. luwang_0925@163.com.
Junfeng MaNational Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun 130012, China. mjf@jlu.edu.cn.ORCID 0000-0002-8914-3125
Xueqi FuNational Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun 130012, China. fxq@jlu.edu.cn.
Jilin University · CN

Funding

Changbai Mountain Research Support Foundation No. 440020031187Changbai Mountain Research Support Foundation No. 440050117010Jilin Province Postdoctoral Science Foundation No. 801161010413National Natural Science Foundation of China No. 31000358National Natural Science Foundation of China No. 31670795the Jilin Province Science and Technology Development Project No. 20180101271JC
6 · The paper itself

Abstract

Amyloid-β, one of the hallmarks of Alzheimer's disease (AD), is toxic to neurons and can also cause brain cell death. Oxidative stress is known to play an important role in AD, and there is strong evidence that oxidative stress is associated with amyloid-β. In the present study we report the protective effect of Zijuan Pu'er tea water extract (ZTWE) and the mixture of main ingredients (+)-catechins, caffeine and procyanidin (MCCP) in ZTWE on β-amyloid-induced toxicity in transgenic

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsAnimals, Genetically ModifiedAntioxidantsBiflavonoidsCaenorhabditis elegansCaffeineCatechinDisease Models, AnimalGene Expression RegulationHumansOxidative StressParalysisPlant ExtractsProanthocyanidinsAmyloid beta-PeptidesAntioxidantsBiflavonoidsCaffeineCatechinPlant ExtractsProanthocyanidinsprocyanidinReactive Oxygen SpeciesSuperoxide DismutaseTeaAlzheimer’s diseaseamyloid-βC. elegansoxidative stress

Identifiers

PMID30781621
PMCPMC6412921
OpenAlexW2912583135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.