Evidence map›Paper›PMID 30781555›Full record

ReviewCells2019

Exosome in Cardiovascular Diseases: A Complex World Full of Hope.

Gloria Bellin, Chiara Gardin, Letizia Ferroni, Juan Carlos Chachques, Massimo Rogante, Dinko Mitrečić, Roberto Ferrari, Barbara Zavan

Abstract readReview
In one paragraph

Review in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed.

  1. Engineered NestinJournal of extracellular vesicles · 2026
    Article
  2. Comparison of Methods for the Isolation of Salivary Extracellular Vesicles.International journal of molecular sciences · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Circulating Extracellular Vesicles in Cardiovascular Disease.International journal of molecular sciences · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Role of Exosomes in Cardiovascular Diseases.Reviews in cardiovascular medicine · 2024
    Review
  19. Development of stem cell therapy for atherosclerosis.Molecular and cellular biochemistry · 2024
    Review
  20. Review

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gloria BellinDepartment of Biomedical Sciences, University of Padova, 35131 Padua, Italy. gloria.bellin@gmail.com.ORCID 0000-0001-7932-3205
Chiara GardinDepartment of Biomedical Sciences, University of Padova, 35131 Padua, Italy. chiara.gardin@unipd.it.
Letizia FerroniDepartment of Biomedical Sciences, University of Padova, 35131 Padua, Italy. letizia.ferroni@unipd.it.
Juan Carlos ChachquesLaboratory of Biosurgical Research (Alain Carpentier Foundation), Pompidu Hospital, University Paris Descartes, 75015 Paris, France. j.chachques-ext@aphp.fr.
Massimo RoganteRogante Engineering Office, 62012 Civitanova Marche, Italy. main@roganteengineering.it.ORCID 0000-0002-6846-0826
Dinko MitrečićLaboratory for Stem Cells, Croatian Institute for Brain Research, University of Zagreb School of Medicine, 10000 Zagreb, Croatia. dinko.mitrecic@mef.hr.
Roberto FerrariMaria Cecilia Hospital, GVM Care & Research, 48033 Ravenna, Italy. fri@unife.it.
Barbara ZavanDepartment of Biomedical Sciences, University of Padova, 35131 Padua, Italy. barbara.zavan@unipd.it.ORCID 0000-0002-4779-4456

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exosomes are a subgroup of extracellular vesicles containing a huge number of bioactive molecules. They represent an important means of cell communication, mostly between different cell populations, with the purpose of maintaining tissue homeostasis and coordinating the adaptive response to stress. This type of intercellular communication is important in the cardiovascular field, mainly due to the fact that the heart is a complex multicellular system. Given the growing interest in the role of exosomes in cardiovascular diseases and the numerous studies published in the last few decades, we focused on the most relevant results about exosomes in the cardiovascular filed starting from their characterization, passing through the study of their function, and ending with perspectives for their use in cardiovascular therapies.

Indexed as

BiomarkersCardiovascular DiseasesExosomesHumansModels, BiologicalMyocardiumBiomarkerscardiovascular diseaseexosomesextracellular vesicle

Identifiers

PMID30781555
PMCPMC6406975

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.