Evidence map›Paper›PMID 30781372›Full record

ArticleInternational journal of molecular sciences2019

Osseointegration of Alkali-Modified NANOZR Implants: An In Vivo Study.

Satoshi Komasa, Mariko Nishizaki, Honghao Zhang, Seiji Takao, Derong Yin, Chisato Terada, Yasuyuki Kobayashi, Tetsuji Kusumoto, Shigeki Yoshimine, Hiroshi Nishizaki and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. An engineering perspective of ceramics applied in dental reconstructions.Journal of applied oral science : revista FOB · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Satoshi KomasaDepartment of Removable Prosthodontics and Occlusion, Osaka Dental University, 8-1, Kuzuhahanazono-cho, Hirakata-shi, Osaka 5731121, Japan. komasa-s@cc.osaka-dent.ac.jp.ORCID 0000-0001-5400-8479
Mariko NishizakiDepartment of Removable Prosthodontics and Occlusion, Osaka Dental University, 8-1, Kuzuhahanazono-cho, Hirakata-shi, Osaka 5731121, Japan. nishizaki-m@cc.osaka-dent.ac.jp.ORCID 0000-0002-5376-179X
Honghao ZhangDepartment of Removable Prosthodontics and Occlusion, Osaka Dental University, 8-1, Kuzuhahanazono-cho, Hirakata-shi, Osaka 5731121, Japan. joecheung_asuka@hotmail.com.
Seiji TakaoDepartment of Removable Prosthodontics and Occlusion, Osaka Dental University, 8-1, Kuzuhahanazono-cho, Hirakata-shi, Osaka 5731121, Japan. takao-s@cc.osaka-dent.ac.jp.
Derong YinDepartment of Removable Prosthodontics and Occlusion, Osaka Dental University, 8-1, Kuzuhahanazono-cho, Hirakata-shi, Osaka 5731121, Japan. yin-d@cc.osaka-dent.ac.jp.
Chisato TeradaDepartment of Removable Prosthodontics and Occlusion, Osaka Dental University, 8-1, Kuzuhahanazono-cho, Hirakata-shi, Osaka 5731121, Japan. terada-c@cc.osaka-dent.ac.jp.
Yasuyuki KobayashiOsaka Research Institute of Industrial Science and Technology Morinomiya Center, 1-6-50, Morinomiya, Joto-ku, Osaka-shi 5368553, Japan. kobaya@omtri.or.jp.
Tetsuji KusumotoOsaka Dental University Japan Faculty of Health Sciences, 1-4-4, Makino-honmachi, Hirakata-shi, Osaka 5731144, Japan. kusumoto@cc.osaka-dent.ac.jp.
Shigeki YoshimineDepartment of Removable Prosthodontics and Occlusion, Osaka Dental University, 8-1, Kuzuhahanazono-cho, Hirakata-shi, Osaka 5731121, Japan. yosimine@cc.osaka-dent.ac.jp.
Hiroshi NishizakiOsaka Dental University Japan Faculty of Health Sciences, 1-4-4, Makino-honmachi, Hirakata-shi, Osaka 5731144, Japan. nisizaki@cc.osaka-dent.ac.jp.ORCID 0000-0001-6778-6915
Joji OkazakiDepartment of Removable Prosthodontics and Occlusion, Osaka Dental University, 8-1, Kuzuhahanazono-cho, Hirakata-shi, Osaka 5731121, Japan. joji@cc.osaka-dent.ac.jp.
Luyuan ChenDepartment of Removable Prosthodontics and Occlusion, Osaka Dental University, 8-1, Kuzuhahanazono-cho, Hirakata-shi, Osaka 5731121, Japan. chen-luyuan900115@foxmail.com.
Osaka Dental University · JPOsaka Research Institute of Industrial Science and Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ingredients and surface modification methods are being continually developed to improve osseointegration of dental implants and reduce healing times. In this study, we demonstrate in vitro that, by applying concentrated alkali treatment to NANOZR with strong bending strength and fracture toughness, a significant improvement in the bone differentiation of rat bone marrow cells can be achieved. We investigated the influence of materials modified with this treatment in vivo, on implanted surrounding tissues using polychrome sequential fluorescent labeling and micro-computer tomography scanning. NANOZR implant screws in the alkali-treated group and the untreated group were evaluated after implantation in the femur of Sprague⁻Dawley male rats, indicating that the amount of new bone in the alkali-modified NANOZR was higher than that of unmodified NANOZR. Alkali-modified NANOZR implants proved to be useful for the creation of new implant materials.

Indexed as

Implants, ExperimentalAlkaliesAnimalsBone and BonesCell DifferentiationMaleNanocompositesOsseointegrationOsteogenesisPhotoelectron SpectroscopyRatsSurface PropertiesX-Ray MicrotomographyZirconiumAlkaliesZirconiumzirconium oxidealkali treatmentin vivo studyNANOZR

Identifiers

PMID30781372
PMCPMC6413168
OpenAlexW2913191059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.