Evidence map›Paper›PMID 30781366›Full record

ReviewPharmaceuticals (Basel, Switzerland)2019

Iron in Lung Pathology.

Vida Zhang, Elizabeta Nemeth, Airie Kim

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
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  3. Review
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  6. Article
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  9. Article
  10. Review
  11. Article
  12. Lactoferrin: from the structure to the functional orchestration of iron homeostasis.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Vida ZhangDepartment of Molecular and Medical Pharmacology, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA. vzhang@mednet.ucla.edu.
Elizabeta NemethDepartment of Medicine, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA. enemeth@mednet.ucla.edu.
Airie KimDepartment of Medicine, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA. airiekim@mednet.ucla.edu.
University of California, Los Angeles · US

Funding

Ferroportin Structure and functionR01DK107309 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JORMAKKA, MIKA, MACKENZIE, BRYAN · 2015 to 2019
$3.0M
Acute Anemia of Inflammation: Mechanisms and Novel TherapiesK08HL127293 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KIM, AIRIE · 2015 to 2019
$824k
NHLBI NIH HHS K08 HL127293NHLBI NIH HHS K08-HL127293NIDDK NIH HHS R01 DK107309
6 · The paper itself

Abstract

The lung presents a unique challenge for iron homeostasis. The entire airway is in direct contact with the environment and its iron particulate matter and iron-utilizing microbes. However, the homeostatic and adaptive mechanisms of pulmonary iron regulation are poorly understood. This review provides an overview of systemic and local lung iron regulation, as well as the roles of iron in the development of lung infections, airway disease, and lung injury. These mechanisms provide an important foundation for the ongoing development of therapeutic applications.

Indexed as

acute lung injuryCOPDcystic fibrosishepcidinironlunglung infection

Identifiers

PMID30781366
PMCPMC6469192
OpenAlexW2913793261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.