Evidence map›Paper›PMID 30779937›Full record

ArticleMolecular and cellular endocrinology2019

TNF-alpha inhibits pregnancy-adapted Ca

Amanda C Ampey, Derek S Boeldt, Luca Clemente, Mary A Grummer, FuXian Yi, Ronald R Magness, Ian M Bird

Abstract read
In one paragraph

Article in Molecular and cellular endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  6. Mononuclear Cells Negatively Regulate Endothelial CaReproductive sciences (Thousand Oaks, Calif.) · 2023
    Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amanda C AmpeyPerinatal Research Laboratories, Department of Obstetrics and Gynecology, School Medicine and Public Health, University of Wisconsin-Madison, 7E Unity Point Health-Meriter Hospital, 202 South Park Street, Madison, WI, 53715, USA.
Derek S BoeldtPerinatal Research Laboratories, Department of Obstetrics and Gynecology, School Medicine and Public Health, University of Wisconsin-Madison, 7E Unity Point Health-Meriter Hospital, 202 South Park Street, Madison, WI, 53715, USA.
Luca ClementePerinatal Research Laboratories, Department of Obstetrics and Gynecology, School Medicine and Public Health, University of Wisconsin-Madison, 7E Unity Point Health-Meriter Hospital, 202 South Park Street, Madison, WI, 53715, USA.
Mary A GrummerPerinatal Research Laboratories, Department of Obstetrics and Gynecology, School Medicine and Public Health, University of Wisconsin-Madison, 7E Unity Point Health-Meriter Hospital, 202 South Park Street, Madison, WI, 53715, USA.
FuXian YiPerinatal Research Laboratories, Department of Obstetrics and Gynecology, School Medicine and Public Health, University of Wisconsin-Madison, 7E Unity Point Health-Meriter Hospital, 202 South Park Street, Madison, WI, 53715, USA.
Ronald R MagnessPerinatal Research Laboratories, Department of Obstetrics and Gynecology, School Medicine and Public Health, University of Wisconsin-Madison, 7E Unity Point Health-Meriter Hospital, 202 South Park Street, Madison, WI, 53715, USA.
Ian M BirdPerinatal Research Laboratories, Department of Obstetrics and Gynecology, School Medicine and Public Health, University of Wisconsin-Madison, 7E Unity Point Health-Meriter Hospital, 202 South Park Street, Madison, WI, 53715, USA. Electronic address: imbird@wisc.edu.

Funding

Unified Cellular and Molecular CoreP01HD038843 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI ZHENG, JING · 2001 to 2017
$14.4M
Endocrinology-Reproductive Physiology Training GrantT32HD041921 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI BIRD, IAN M. · 2004 to 2022
$3.0M
Endothelial Function in a Model of IUGR Induced by Uterine Space RestrictionR01HL117341 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MAGNESS, RONALD R · 2014 to 2017
$1.8M
NHLBI NIH HHS R01 HL117341NICHD NIH HHS P01 HD038843NICHD NIH HHS T32 HD041921
6 · The paper itself

Abstract

Enhancement of vasodilation of uterine arteries during pregnancy occurs through increased connexin (Cx)43 gap junction (GJ) communication supporting more frequent and sustained Ca

Indexed as

Adenosine TriphosphateAnimalsButadienesCalciumCalcium SignalingConnexin 43Endothelial CellsEndothelium, VascularFemaleHumansMAP Kinase Signaling SystemNitric OxideNitrilesPhosphorylationPhosphoserinePhosphotyrosineAdenosine TriphosphateAG 1879ButadienesCalciumConnexin 43Nitric OxideNitrilesPhosphoserinePhosphotyrosineProtein Kinase InhibitorsPyrimidinesReactive Oxygen Speciessrc-Family KinasesTumor Necrosis Factor-alphaU 0126Vascular Endothelial Growth Factor ACa(2+)Endothelial dysfunctionGap junctionPregnancySrcTNF-Alpha

Identifiers

PMID30779937
PMCPMC6475486

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.