Evidence map›Paper›PMID 30779800›Full record

ArticlePloS one2019

Identification of suicidal behavior among psychiatrically hospitalized adolescents using natural language processing and machine learning of electronic health records.

Nicholas J Carson, Brian Mullin, Maria Jose Sanchez, Frederick Lu, Kelly Yang, Michelle Menezes, Benjamin Lê Cook

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 6 pooled it
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 6 syntheses or guidelines pooled it, 116 citations in OpenAlex.

  1. Pooled it
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  6. Artificial Intelligence and Suicide Prevention: A Systematic Review of Machine Learning Investigations.International journal of environmental research and public health · 2020
    Pooled it
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  17. Detection of suicidality from medical text using privacy-preserving large language models.The British journal of psychiatry : the journal of mental science · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nicholas J CarsonHealth Equity Research Lab, Cambridge Health Alliance, Cambridge, MA, United States of America.ORCID 0000-0002-4601-8279
Brian MullinHealth Equity Research Lab, Cambridge Health Alliance, Cambridge, MA, United States of America.
Maria Jose SanchezHealth Equity Research Lab, Cambridge Health Alliance, Cambridge, MA, United States of America.ORCID 0000-0001-8551-1368
Frederick LuHealth Equity Research Lab, Cambridge Health Alliance, Cambridge, MA, United States of America.ORCID 0000-0002-9884-8231
Kelly YangHealth Equity Research Lab, Cambridge Health Alliance, Cambridge, MA, United States of America.
Michelle MenezesHealth Equity Research Lab, Cambridge Health Alliance, Cambridge, MA, United States of America.
Benjamin Lê CookHealth Equity Research Lab, Cambridge Health Alliance, Cambridge, MA, United States of America.
Cambridge Health Alliance · US

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
NCATS NIH HHS UL1 TR001102
6 · The paper itself

Abstract

objectiveThe rapid proliferation of machine learning research using electronic health records to classify healthcare outcomes offers an opportunity to address the pressing public health problem of adolescent suicidal behavior. We describe the development and evaluation of a machine learning algorithm using natural language processing of electronic health records to identify suicidal behavior among psychiatrically hospitalized adolescents.

methodsAdolescents hospitalized on a psychiatric inpatient unit in a community health system in the northeastern United States were surveyed for history of suicide attempt in the past 12 months. A total of 73 respondents had electronic health records available prior to the index psychiatric admission. Unstructured clinical notes were downloaded from the year preceding the index inpatient admission. Natural language processing identified phrases from the notes associated with the suicide attempt outcome. We enriched this group of phrases with a clinically focused list of terms representing known risk and protective factors for suicide attempt in adolescents. We then applied the random forest machine learning algorithm to develop a classification model. The model performance was evaluated using sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy.

resultsThe final model had a sensitivity of 0.83, specificity of 0.22, AUC of 0.68, a PPV of 0.42, NPV of 0.67, and an accuracy of 0.47. The terms mostly highly associated with suicide attempt clustered around terms related to suicide, family members, psychiatric disorders, and psychotropic medications.

conclusionThis analysis demonstrates modest success of a natural language processing and machine learning approach to identifying suicide attempt among a small sample of hospitalized adolescents in a psychiatric setting.

Indexed as

Adolescent BehaviorMachine LearningNatural Language ProcessingSuicidal IdeationAdolescentAdolescent, HospitalizedAlgorithmsChildElectronic Health RecordsFemaleHumansMaleMassachusettsPsychiatric Department, HospitalPsychology, AdolescentSuicide, Attempted

Identifiers

PMID30779800
PMCPMC6380543
OpenAlexW2916778535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.