ArticleAging2019
Age and poverty status alter the coding and noncoding transcriptome.
Article in Aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- Association of mitochondrial DNA haplogroup, oxidative DNA damage and inflammatory markers in middle-aged adults.International journal of radiation biology · 2026Article
- The interface of geroscience with longitudinal health disparities research: a 20-year retrospective of the Healthy Aging in Neighborhoods of Diversity across the Life Span study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Article
- Genome-wide transcriptome differences associated with perceived discrimination in an urban, community-dwelling middle-aged cohort.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- Association of extracellular vesicle inflammatory proteins and mortality.Scientific reports · 2022Article
- The accelerated aging phenotype: The role of race and social determinants of health on aging.Ageing research reviews · 2022Review
- Host-virus interaction and viral evasion.Cell biology international · 2021Review
- African Americans and European Americans exhibit distinct gene expression patterns across tissues and tumors associated with immunologic functions and environmental exposures.Scientific reports · 2021Article
- Article
- Ageing-associated changes in the expression of lncRNAs in human tissues reflect a transcriptional modulation in ageing pathways.Mechanisms of ageing and development · 2020Article
- Health Disparities in COVID-19: Addressing the Role of Social Determinants of Health in Immune System Dysfunction to Turn the Tide.Frontiers in public health · 2020Article
- Non-coding RNAs as Regulators of Cellular Senescence in Idiopathic Pulmonary Fibrosis and Chronic Obstructive Pulmonary Disease.Frontiers in medicine · 2020Review
- The association between poverty and gene expression within peripheral blood mononuclear cells in a diverse Baltimore City cohort.PloS one · 2020Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Emerging evidence indicates that noncoding RNAs play regulatory roles in aging and disease. The functional roles of long noncoding RNAs (lncRNAs) in physiology and disease are not completely understood. Little is known about lncRNAs in the context of human aging and socio-environmental conditions. Microarray profiling of lncRNAs and mRNAs from peripheral blood mononuclear cells from young and old white (n=16) and African American (AA) males (n=16) living above or below poverty from the Healthy Aging in Neighborhoods of Diversity across the Life Span study revealed changes in both lncRNAs and mRNAs with age and poverty status in white males, but not in AA males. We validated lncRNA changes in an expanded cohort (n=40);
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.