ArticleHuman vaccines & immunotherapeutics2019
Outbreak of mumps in a student population with high vaccination coverage in China: time for two-dose vaccination.
Article in Human vaccines & immunotherapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Epidemiological trends and determinants of mumps outbreaks: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Incremental effectiveness of the second dose of mumps-containing vaccine among children 9 months to 6 years in Hefei: A matched case-control study.Human vaccines & immunotherapeutics · 2025Article
- Antibody Levels Against Mumps Virus in Children After Implementation of the Two-Dose MMR Vaccine Policy - Fujian Province, China, 2023.China CDC weekly · 2025Article
- Development and characterization of the genotype F attenuated mumps candidate strains.Frontiers in immunology · 2025Article
- Risk factors for mumps in children under 15 years of age during the transition from single-dose to two-dose MMR vaccination strategy: a matched case-control study.Frontiers in public health · 2025Article
- Epidemiological characteristics and interrupted time series analysis of mumps in Quzhou City, 2005-2023.Human vaccines & immunotherapeutics · 2024Article
- Assessment of mumps-containing vaccine effectiveness by dose during 2006 to 2020 in Quzhou, China.Human vaccines & immunotherapeutics · 2022Article
- Preponderance of vaccine-preventable diseases hotspots in northern Ghana: a spatial and space-time clustering analysis from 2010 to 2014.BMC public health · 2022Article
- A Multi-Age-Group Interrupted Time-Series Study for Evaluating the Effectiveness of National Expanded Program on Immunization on Mumps.Vaccines · 2022Article
- Loss of protective immunity of two-dose mumps-containing vaccine over time: concerns with the new strategy of the mumps immunization program in China.Human vaccines & immunotherapeutics · 2021Article
- Non-linear relationships and interactions of meteorological factors on mumps in Jinan, China.International journal of biometeorology · 2021Article
- Introduction of Two-Dose Mumps-Containing Vaccine into Routine Immunization Schedule in Quzhou, China, Using Cox-Proportional Hazard Model.Journal of immunology research · 2021Article
- Mumps Orchitis: Clinical Aspects and Mechanisms.Frontiers in immunology · 2021Review
- Effects of extreme meteorological factors on daily mumps cases in Hefei, China, during 2011-2016.Environmental science and pollution research international · 2020Article
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In 2016, an outbreak of mumps occurred in a primary school in China with a student population having high vaccination coverage. An unmatched case-control study was performed to identify risk factors contributing to this outbreak, and a retrospective cohort study was conducted to evaluate the effectiveness of mumps-containing vaccine (MuCV). A total of 97 cases were identified during the outbreak, and the overall attack rate was 8.2%. Among students with confirmed vaccination status, 90% had received at least one dose of MuCV. Cases were more likely than non-cases to report taking the school bus during the epidemic period (adjusted OR = 2.3, 95% CI: 1.4-3.7). Vaccine effectiveness (VE) was higher for two-dose MuCV (76%, 95% CI:49â€"89%) than for one-dose MuCV (59%, 95% CI: 36â€"74%. The protection afforded by both one-dose and two-dose MuCV waned over time, from 82% among students vaccinated within 5 years to 41% among those vaccinated more than 10 years previously for one-dose VE, and from 90% to 25% over the same time period for two-dose VE. We found that outbreaks of mumps can occur in schools despite high coverage of one-dose MuCV vaccination. Although the VE of both two-dose and one-dose MuCV wanes over time, the overall VE for two-dose MuCV was superior than that of one-dose MuCV. Therefore, a two-dose MuCV schedule through routine services is likely needed in order to control mumps epidemics in China.
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