ArticleAnalytical chemistry2019
Multiplexed Relative Quantitation with Isobaric Tagging Mass Spectrometry Reveals Class I Major Histocompatibility Complex Ligand Dynamics in Response to Doxorubicin.
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Article in Analytical chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
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Who cites it
21 citing papers in PubMed, 39 citations in OpenAlex.
- AI-powered mapping of tumor immunity for optimized mRNA vaccine engineering.Frontiers in oncology · 2026Review
- Non-canonical and induced neoantigens as emerging sources of cancer-specific immunotherapy targets.Frontiers in immunology · 2026Review
- A New Strategy to Identify Naturally Presenting SLA-I Bound Peptides Derived from the O Serotype of Foot-and-Mouth Disease Virus, by Mild Acid Elution in a VP1 Stably Expressed PK15 Cell Line.Animals : an open access journal from MDPI · 2025Article
- Engineered Proteins and Chemical Tools to Probe the Cell Surface Proteome.Chemical reviews · 2025Review
- Predicting MHC-I ligands across alleles and species: how far can we go?Genome medicine · 2025Article
- Hypoxia promotes tumor immune evasion by suppressing MHC-I expression and antigen presentation.The EMBO journal · 2025Article
- NetMHCpan-4.2: improved prediction of CD8+ epitopes by use of transfer learning and structural features.Frontiers in immunology · 2025Article
- Pan-cancer analysis of T-cell proliferation regulatory genes as potential immunotherapeutic targets.Aging · 2024Article
- The MHC Motif Atlas: a database of MHC binding specificities and ligands.Nucleic acids research · 2023Article
- MEK inhibition enhances presentation of targetable MHC-I tumor antigens in mutant melanomas.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- A comprehensive SARS-CoV-2-human protein-protein interactome network identifies pathobiology and host-targeting therapies for COVID-19.Research square · 2022Article
- Differential responses to immune checkpoint inhibitor dictated by pre-existing differential immune profiles in squamous cell carcinomas caused by same initial oncogenic drivers.Journal of experimental & clinical cancer research : CR · 2022Article
- Immune Checkpoint Blockade Augments Changes Within Oncolytic Virus-induced Cancer MHC-I Peptidome, Creating Novel Antitumor CD8 T Cell Reactivities.Molecular & cellular proteomics : MCP · 2022Article
- Artificial intelligence applied in neoantigen identification facilitates personalized cancer immunotherapy.Frontiers in oncology · 2022Review
- Soluble HLA peptidome: A new resource for cancer biomarkers.Frontiers in oncology · 2022Review
- Article
- 1,2,3, MHC: a review of mass-spectrometry-based immunopeptidomics methods for relative and absolute quantification of pMHCs.Immuno-oncology technology · 2021Review
- A few good peptides: MHC class I-based cancer immunosurveillance and immunoevasion.Nature reviews. Immunology · 2021Review
- Multiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition.Nature communications · 2020Article
- Therapy-Induced MHC I Ligands Shape Neo-Antitumor CD8 T Cell Responses during Oncolytic Virus-Based Cancer Immunotherapy.Journal of proteome research · 2019Article
Corrections and comments
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Authors and funding
14 authors at 5 institutions in 3 countries.
J Patrick MurphyDepartment of Pathology , Dalhousie University , Halifax , Nova Scotia B3H 4R2 , Canada.
Qijia YuDivision of Genomic Stability and DNA Repair, Department of Radiation Oncology , Dana-Farber Cancer Institute , Boston , Massachusetts 02215 , United States.ORCID 0000-0003-0409-7316
Prathyusha KondaDepartment of Microbiology and Immunology , Dalhousie University , Halifax , Nova Scotia B3H 4R2 , Canada.
Joao A PauloDepartment of Cell Biology , Harvard Medical School , Boston , Massachusetts 02115 , United States.
Mark P JedrychowskiDivision of Genomic Stability and DNA Repair, Department of Radiation Oncology , Dana-Farber Cancer Institute , Boston , Massachusetts 02215 , United States.
Daniel J KowalewskiDepartment of Immunology, Interfaculty Institute for Cell Biology , University of Tübingen , 72076 Tübingen , Germany.
Heiko SchusterDepartment of Immunology, Interfaculty Institute for Cell Biology , University of Tübingen , 72076 Tübingen , Germany.
Youra KimDepartment of Pathology , Dalhousie University , Halifax , Nova Scotia B3H 4R2 , Canada.
Derek ClementsDepartment of Pathology , Dalhousie University , Halifax , Nova Scotia B3H 4R2 , Canada.
Aditya JainDivision of Genomic Stability and DNA Repair, Department of Radiation Oncology , Dana-Farber Cancer Institute , Boston , Massachusetts 02215 , United States.
Stefan StevanovicDepartment of Immunology, Interfaculty Institute for Cell Biology , University of Tübingen , 72076 Tübingen , Germany.
Steven P GygiDepartment of Cell Biology , Harvard Medical School , Boston , Massachusetts 02115 , United States.
Joseph D ManciasDivision of Genomic Stability and DNA Repair, Department of Radiation Oncology , Dana-Farber Cancer Institute , Boston , Massachusetts 02215 , United States.
Shashi GujarDepartment of Pathology , Dalhousie University , Halifax , Nova Scotia B3H 4R2 , Canada.ORCID 0000-0002-5427-0829
Dalhousie University · CADana-Farber Cancer Institute · USHarvard University · USImmatics Biotechnologies (Germany) · DEUniversity of Tübingen · DE
Funding
New Sample Multiplexing Technologies to Identify Chemical Probes and Illuminate Ubiquitin BiologyR01GM067945 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI GYGI, STEVEN P · 2003 to 2024
$10.5MAdvancing Multiplexed Isobaric Tag-based Strategies for Proteome ProfilingR01GM132129 · NIGMS · HARVARD MEDICAL SCHOOL · PI PAULO, JOAO A · 2019 to 2023
$1.7MCIHRNIGMS NIH HHS R01 GM067945NIGMS NIH HHS R01 GM132129
Abstract
MHC-I peptides are intracellular-cleaved peptides, usually 8-11 amino acids in length, which are presented on the cell surface and facilitate CD8
Indexed as
AnimalsAntibiotics, AntineoplasticCD8-Positive T-LymphocytesColonic NeoplasmsDoxorubicinDrug DiscoveryHCT116 CellsHistocompatibility Antigens Class IHumansImmunotherapyLigandsLymphomaMass SpectrometryMiceMice, Inbred C57BLTumor Cells, CulturedAntibiotics, AntineoplasticDoxorubicinHistocompatibility Antigens Class ILigands
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.