Evidence map›Paper›PMID 30779431›Full record

ArticleAlcoholism, clinical and experimental research2019

Dose-Response Relationship of Alcohol and Injury Cause: Effects of Country-Level Drinking Pattern and Alcohol Policy.

Cheryl J Cherpitel, Jane Witbrodt, Rachael A Korcha, Yu Ye, Maristela G Monteiro, Patricia Chou

Open access · greenAbstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Do socioeconomic status, race and ethnicity modify the relationship between alcohol use and unintentional injury mortality?Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2025
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  9. Road traffic injury risk from alcohol and cannabis use among emergency department patients in Argentina.Revista panamericana de salud publica = Pan American journal of public health · 2022
    Article
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Cheryl J CherpitelAlcohol Research Group, Emeryville, California.ORCID 0000-0001-6663-3466
Jane WitbrodtAlcohol Research Group, Emeryville, California.
Rachael A KorchaAlcohol Research Group, Emeryville, California.
Yu YeAlcohol Research Group, Emeryville, California.
Maristela G MonteiroPan American Health Organization, Washington, District of Columbia.
Patricia ChouNational Institute on Alcohol Abuse and Alcoholism, Washington, District of Columbia.
Alcohol Research Group · USNational Institute on Alcohol Abuse and Alcoholism · USWorld Health Organization Regional Office for the Americas · US

Funding

Cross-National Analysis of Alcohol & InjuryR01AA013750 · NIAAA · PUBLIC HEALTH INSTITUTE · PI CHERPITEL, CHERYL J · 2002 to 2018
$4.4M
NIAAA NIH HHS R01 AA013750
6 · The paper itself

Abstract

backgroundThe dose-response relationship of alcohol and injury and the effects of country-level detrimental drinking pattern (DDP) and alcohol control policy on this relationship are examined for specific causes of injury.

methodsThe dose-response risk of injury is analyzed on 18,627 injured patients in 22 countries included in the International Collaborative Alcohol and Injury Study, using case-crossover analysis by cause of injury (traffic, violence, falls, other), DDP, and the International Alcohol Policy and Injury Index.

resultsRisk of all injury was higher at all volume levels in higher DDP countries compared to lower DDP countries and for each cause of injury. Risk of injury from traffic was significantly greater in higher DDP than lower DDP countries at 3.1 to 6 drinks (odds ratio (OR) = 2.64, confidence interval (CI) = 1.17 to 5.97) and at ≤3 drinks for falls (OR = 2.51, CI = 1.52 to 4.16) and injuries from other causes (OR = 1.72, CI = 1.10 to 2.69). Countries with higher restrictive alcohol policy were at a lower risk of injury at lower levels of consumption (≤3 drinks) for all injuries (OR = 0.72, CI = 0.56 to 0.92) and for injuries from other causes (OR = 0.46, CI = 0.29 to 0.73) and at a lower risk of traffic injuries at higher levels of consumption (≥10 drinks). At higher levels of consumption (≥10 drinks), countries with higher alcohol policy restrictiveness were at greater risk of all injuries (OR = 2.03, CI = 1.29 to 3.20) and those from violence (OR = 9.02, CI = 3.00 to 27.13) and falls (OR = 4.29, CI = 1.86 to 9.91).

conclusionsCountries with high DDP are at higher risk of injury from most causes at a given level of consumption, while countries with low restrictiveness of alcohol policy are at higher risk of injury at lower levels of consumption and at higher risk of traffic injuries at high levels of consumption. These findings underscore the importance of aggregate-level factors which need to be considered in developing effective intervention and prevention strategies for reducing alcohol-related injury.

Indexed as

Accidental FallsInternationalityAccidents, TrafficAlcohol DrinkingCross-Over StudiesDose-Response Relationship, DrugEmergency Service, HospitalFemaleHumansMalePublic PolicyViolenceCause of InjuryDose-ResponsePolicyRelative Risk

Identifiers

PMID30779431
PMCPMC6502645
OpenAlexW2916276856

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.