Evidence map›Paper›PMID 30779377›Full record

ArticleNeurourology and urodynamics2019

Mechanical impact of parturition-related strains on rat pelvic striated sphincters.

Pamela Duran, Samuel Ward, Karen L Christman, Marianna Alperin

Abstract read
In one paragraph

Article in Neurourology and urodynamics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Pamela DuranDepartment of Bioengineering, Sanford Consortium for Regenerative Medicine, University of California, San Diego, California.
Samuel WardDepartment of Orthopaedic Surgery, University of California, San Diego, California.
Karen L ChristmanDepartment of Bioengineering, Sanford Consortium for Regenerative Medicine, University of California, San Diego, California.
Marianna AlperinDepartment of Obstetrics, Gynecology and Reproductive Sciences, Division of Female Pelvic Medicine and Reconstructive Surgery, University of California, San Diego, California.ORCID 0000-0002-6004-1803
University of California San Diego · USUniversity of California System · US

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
UC San Diego Womens Reproductive Health Research ProgramK12HD001259 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CYNTHIA GYAMFI-BANNERMAN · 1999 to 2026
$9.1M
Mechanisms and Impact of Pregnancy-Induced Adaptations in Pelvic Floor MusclesR01HD092515 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ALPERIN, MARIANNA · 2017 to 2025
$4.0M
Pathways underlying recovery of injured urethral sphincter and a novel regenerative biomaterial interventionR01DK128639 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ALPERIN, MARIANNA, CHRISTMAN, KAREN L · 2021 to 2024
$2.2M
Predoctoral Training in Translational Musculoskeletal ResearchT32AR060712 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LIEBER, RICHARD L., SAH, ROBERT L · 2012 to 2016
$741k
Injectable Tissue-Specific Extracellular Matrix Hydrogel for Pelvic Skeletal Muscle Regeneration Following Birth InjuryR21HD094566 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ALPERIN, MARIANNA, CHRISTMAN, KAREN L · 2018 to 2019
$426k
Impact of Aging on Structure and Function of Pelvic Floor MusclesR03AG050951 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ALPERIN, MARIANNA · 2016 to 2017
$233k
NCATS NIH HHS UL1 TR001442NIAMS NIH HHS T32 AR060712NIA NIH HHS R03 AG050951NICHD NIH HHS K12 HD001259NICHD NIH HHS R01 HD092515NICHD NIH HHS R21 HD094566NIDDK NIH HHS R01 DK128639
6 · The paper itself

Abstract

aimsTo define the operational resting sarcomere length (L

methodsEUS and EAS of 3-month-old Sprague-Dawley control and injured rats were fixed in situ, harvested, and microdissected for L

resultsThe operational resting L

conclusionsAnalogous to humans, the short resting L

Indexed as

ParturitionAnal CanalAnimalsDelivery, ObstetricFemaleManometryMuscle, StriatedMyofibrilsPelvic FloorPregnancyRatsRats, Sprague-DawleyRectumSarcomeresUrinary Incontinence, StressVaginabirth injuryexternal anal sphincterexternal urethral sphincterfecal incontinenceratstress urinary incontinence

Identifiers

PMID30779377
PMCPMC6431564
OpenAlexW2917400245

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.