Evidence map›Paper›PMID 30778838›Full record

ArticleMolecular and cellular biochemistry2019

Hydrogen sulfide modulates SIRT1 and suppresses oxidative stress in diabetic nephropathy.

Hanan H Ahmed, Fatma M Taha, Heba S Omar, Heba M Elwi, Marwa Abdelnasser

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular and cellular biochemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Effects of drinking natural hydrogen sulfide (HInternational journal of biometeorology · 2020
    Pooled it
  2. Review
  3. Article
  4. Sulfide regulation and catabolism in health and disease.Signal transduction and targeted therapy · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Hydrogen Sulfide and the Immune System.Advances in experimental medicine and biology · 2021
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hanan H AhmedMedical Biochemistry and Molecular Biology Department, Kasr Al Ainy School of Medicine, Cairo University, Kasr Al Ainy St., El Manial, 11562, Cairo, Egypt.
Fatma M TahaMedical Biochemistry and Molecular Biology Department, Kasr Al Ainy School of Medicine, Cairo University, Kasr Al Ainy St., El Manial, 11562, Cairo, Egypt.
Heba S OmarMedical Biochemistry and Molecular Biology Department, Kasr Al Ainy School of Medicine, Cairo University, Kasr Al Ainy St., El Manial, 11562, Cairo, Egypt. hebasomar@gmail.com.ORCID http://orcid.org/0000-0002-2887-5007
Heba M ElwiMedical Biochemistry and Molecular Biology Department, Kasr Al Ainy School of Medicine, Cairo University, Kasr Al Ainy St., El Manial, 11562, Cairo, Egypt.
Marwa AbdelnasserPathology Department, Kasr Al Ainy School of Medicine, Cairo University, Kasr Al Ainy St., El Manial, 11562, Cairo, Egypt.
Cairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DN is recognized as not only a leading cause of end stage renal disease (ESRD) but also an independent risk factor for cardiovascular disease (CVD). Novel therapeutic approaches to diabetic nephropathy (DN) are needed, or else, healthcare resources will be overwhelmed by the expected worldwide increase in associated cases of ESRD and CVD. Reactive oxygen species (ROS) and advanced glycation end product (AGE) are implicated in the development of DN. Hydrogen sulfide (H

Indexed as

AnimalsApoptosisDiabetic NephropathiesGene Expression Regulation, EnzymologicHydrogen SulfideKidneyMaleOxidative StressRatsReactive Oxygen SpeciesSirtuin 1Up-RegulationHydrogen SulfideReactive Oxygen SpeciesSirt1 protein, ratSirtuin 1Caspase 3Diabetic nephropathyH2SSIRT1SOD

Identifiers

PMID30778838
OpenAlexW2916588528

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.