Evidence map›Paper›PMID 30778817›Full record

ArticleJournal of cancer survivorship : research and practice2019

Hospitalization rate in offspring of cancer survivors: a national cohort study.

Jianguang Ji, Wuqing Huang, Jan Sundquist, Kristina Sundquist

Open access · hybridAbstract read
In one paragraph

Article in Journal of cancer survivorship : research and practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Jianguang JiCenter for Primary Health Care Research, Lund University/Region Skåne, Malmö University Hospital, CRC, floor 11, building 28, entrance 72, 205 02, Malmö, Sweden. jianguang.ji@med.lu.se.ORCID 0000-0003-0324-9496
Wuqing HuangCenter for Primary Health Care Research, Lund University/Region Skåne, Malmö University Hospital, CRC, floor 11, building 28, entrance 72, 205 02, Malmö, Sweden.
Jan SundquistCenter for Primary Health Care Research, Lund University/Region Skåne, Malmö University Hospital, CRC, floor 11, building 28, entrance 72, 205 02, Malmö, Sweden.
Kristina SundquistCenter for Primary Health Care Research, Lund University/Region Skåne, Malmö University Hospital, CRC, floor 11, building 28, entrance 72, 205 02, Malmö, Sweden.
Malmö University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe number of childbirths among cancer survivors continues to increase, but it is still largely unknown whether the children of cancer survivors might experience adverse health outcomes during the process of growing up.

methodsWe identified all individuals diagnosed with cancer between 1958 and 2015 from the Swedish Cancer Registry and linked them to the Swedish Medical Birth Register to identify their offspring born between 1997 and 2015. Up to 10 children, whose parents did not have a diagnosis of cancer, were matched with the study population according to date of birth and gender.

resultsBy linking with the Swedish Hospital Discharge Register, we found that the hospitalization rate was 15% higher in offspring of female cancer survivors, and 16% higher in offspring of male cancer survivors as compared to matched controls. Besides an increased risk of hospitalization due to malignant neoplasms (relative risk (RR) = 1.86, 99% CI 1.70-2.04) and benign neoplasms (RR = 1.48, 99% CI 1.18-1.86), a non-significant increased risk was found for hospitalization due to infectious and parasitic disease (RR = 1.09, 99% CI 0.98-1.21), diseases of the blood and blood-forming organs and certain disorders involving the immune mechanisms (RR = 1.33, 99% CI 0.98-1.80), and diseases of the circulatory system (RR = 1.05, 99% CI 0.98-1.12).

conclusionOur study suggests that children of cancer survivors might experience a significantly increased rate of hospitalization, which calls for further studies. IMPLICATIONS FOR CANCER SURVIVORS: Cancer survivors might be aware that the risk of hospitalization due to various diseases might be higher in their children as compared to the normal population.

Indexed as

Cancer SurvivorsNeoplasmsAdolescentAdultCase-Control StudiesChildChild of Impaired ParentsChild, PreschoolCohort StudiesFemaleHospitalizationHumansMaleRegistriesRiskSwedenCancer survivorCohort studyEpidemiologyHospitalization rate

Identifiers

PMID30778817
PMCPMC6482289
OpenAlexW2915398857

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.