Evidence map›Paper›PMID 30778816›Full record

ArticleMolecular diversity2020

One-pot organocatalytic/multicomponent approach for the preparation of novel enantioenriched non-natural selenium-based peptoids and peptide-peptoid conjugates.

Alexander F de la Torre, Akbar Ali, Fábio Z Galetto, Antonio L Braga, José A C Delgado, Márcio W Paixão

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Article in Molecular diversity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexander F de la TorreDepartamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Concepción, Edmundo Larenas 234-interior -Casilla 160-C, Concepción, Chile. afernandezd@udec.cl.ORCID http://orcid.org/0000-0003-4767-5868
Akbar AliDepartment of Chemistry, University of Sargodha, Sargodha, 40100, Pakistan.
Fábio Z GalettoDepartamento de Química, Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
Antonio L BragaDepartamento de Química, Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil. braga.antonio@ufsc.br.
José A C DelgadoCenter of Excellence for Research in Sustainable Chemistry (CERSusChem), Department of Chemistry, Federal University of São Carlos - UFSCar, Rodovia Washington Luís, km 235 - SP-310, São Carlos, São Paulo, 13565-905, Brazil.
Márcio W PaixãoCenter of Excellence for Research in Sustainable Chemistry (CERSusChem), Department of Chemistry, Federal University of São Carlos - UFSCar, Rodovia Washington Luís, km 235 - SP-310, São Carlos, São Paulo, 13565-905, Brazil. marelloweber@gmail.com.

Funding

CNPq CNPq (14/403846)Fondecyt 3170003
6 · The paper itself

Abstract

A combined organocatalytic and multicomponent synthetic approach was designed for the preparation of selenium-based peptoids and peptide-peptoid conjugates. This single-step synthetic protocol comprises the organocatalytic asymmetric insertion of phenylselenium in the aldehyde moiety followed by the Ugi four-component reaction which results in obtaining the desired compounds in good-to-moderate yields and with good-to-excellent levels of stereoselectivity.

Indexed as

Chemistry Techniques, SyntheticOrganic Chemistry PhenomenaSeleniumMagnetic Resonance SpectroscopyPeptoidsPeptoidsSeleniumMulticomponent reactionsOrganocatalysisPeptoidsSelenocysteineUgi reaction

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.