ArticleTechniques in coloproctology2019
Botox treatment in patients with chronic functional anorectal pain: experiences of a tertiary referral proctology clinic.
Article in Techniques in coloproctology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- Pelvic floor physical therapy in patients with chronic anal fissure: a randomized controlled trial.Techniques in coloproctology · 2022Trial
- Botulinum Toxin A Use in the Gastrointestinal Tract: A Reappraisal After Three Decades.Gastroenterology & hepatology · 2023Article
- Pelvic floor dysfunction and chronic anal fissure: a dog chasing its tail.Techniques in coloproctology · 2022Article
- Percutaneous Tibial Nerve Stimulation in Chronic Post-Surgical Anorectal Pain: A Case Report.GE Portuguese journal of gastroenterology · 2022Article
- Comparison of botulinum toxin (BoNT) injection and lateral internal sphincterotomy (redo-LIS) for recurrent anal fissure treatment.Frontiers in surgery · 2022Article
- Pelvic floor physical therapy in the treatment of chronic anal fissure (PAF-study): Study protocol for a randomized controlled trial.Contemporary clinical trials communications · 2021Article
- Proctalgia Syndromes: Update in Diagnosis and Management.Current gastroenterology reports · 2020Review
- Levator ani spasm: what to do after biofeedback fails.Techniques in coloproctology · 2020Article
- Botulinum toxin A versus electrogalvanic stimulation for levator ani syndrome: is one a more effective therapy?Techniques in coloproctology · 2020Article
- Therapeutic properties of botulinum toxin on chronic anal fissure treatment and the patient factors role.Journal of family medicine and primary care · 2020Article
- Impaired Anorectal Afferents Is a Potential Pathophysiological Factor Associated to Functional Anorectal Pain.Frontiers in neurology · 2020Article
- Editorial: Botox for levator ani.Techniques in coloproctology · 2019Article
- A comprehensive treatment algorithm for chronic pelvic pain patients: A perspective review and future guidelines.Women's health (London, England)Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnorectal pain is a symptom which may have both structural and functional causes, and can, sometimes, develop into a chronic pain syndrome. Functional causes in particular are challenging to treat when conservative treatment measures fail. Botulinum toxin A (BTX-A) can be applied to relax the anal sphincter and/or levator ani muscle to break the vicious circle of pain and contraction. In our tertiary referral proctology clinic, we evaluated the outcome of patients treated with BTX-A for chronic functional anorectal pain.
methodsOur electronic database was searched for patients who had BTX-A treatment for chronic functional anorectal pain from 2011 to 2016. All medical data concerning history, treatments, and clinical outcome were retrieved. The clinical outcome (resolution of pain) was scored as good, temporary, or poor.
resultsA total of 113 patients [47 (42%) males; age 51years, SD 13 years, range 18-88 years] with chronic functional anorectal pain were included. The outcome of BTX-A treatment was good in 53 (47%), temporary in 23 (20%), and poor in 37 (33%). To achieve this outcome, 29 (45%) patients needed a single treatment, 11 (44%) a second treatment, and 13 (54%) ≥ 3 treatments.
conclusionsChronic functional anorectal pain can be treated successfully with BTX-A in 47% of patients who fail conservative management. Repeated injections may be needed to ensure complete cure in a subgroup of patients.
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