ArticleClinical and experimental nephrology2019
Predictors of withdrawal from renal replacement therapy among patients with acute kidney injury requiring renal replacement therapy.
Article in Clinical and experimental nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Prospective model for predicting renal recovery in cardiac surgery patients with acute kidney injury requiring renal replacement therapy.Nephrology (Carlton, Vic.) · 2021Trial
- Construction and evaluation of prediction model for renal function recovery in acute kidney injury patients undergoing continuous renal replacement therapy based on machine learning algorithms.Annals of medicine · 2025Article
- Risk prediction models for successful discontinuation in acute kidney injury undergoing continuous renal replacement therapy.iScience · 2024Article
- Association between the mean perfusion pressure and the risk of acute kidney injury in critically ill patients with sepsis: a retrospective cohort study.BMC infectious diseases · 2024Article
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3 authors.
Funding
Abstract
backgroundAlthough recovery of renal function after an episode of acute kidney injury (AKI) is an important clinical measure of morbidity, predictors of withdrawal from renal replacement therapy (RRT) among AKI patients remain unclear.
methodsIn this single-center retrospective cohort study, we examined the clinical records of AKI patients requiring RRT who were hospitalized in the ICU or general wards at our hospital from January 2010 to December 2013. A priori-determined covariates of age, sex, cardiovascular disease, chronic kidney disease (CKD), mean arterial pressure (MAP), sepsis, nephrotoxic agents, and hypoalbuminemia were assessed in Cox hazard models to estimate hazard ratio (HR).
resultsA total of 334 patients were enrolled (median age, 68 years; interquartile range [IQR], 57-77 years; male, 71.6%). During follow-up 157 (47.0%) patients achieved RRT withdrawal. Multivariable Cox regression analysis revealed that CKD, MAP between 95 and 105 mmHg and MAP ≥ 105 mmHg, compared with MAP between 65 and 75 mmHg, ventilator use and hypoalbuminemia, were significantly associated with RRT withdrawal.
conclusionAmong patients with AKI requiring RRT, CKD, ventilator use, hypoalbuminemia, and high MAP were associated with RRT withdrawal. Furthermore, keeping a higher MAP at RRT initiation can potentially lead to dependence on RRT.
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