Evidence map›Paper›PMID 30778742›Full record

Trial reportJournal of occupational rehabilitation2019

Two-Year Follow-Up of a Multi-centre Randomized Controlled Trial to Study Effectiveness of a Hospital-Based Work Support Intervention for Cancer Patients.

S J Tamminga, J H A M Verbeek, M M E M Bos, G Fons, J J E M Kitzen, P W Plaisier, M H W Frings-Dresen, A G E M de Boer

Open access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of occupational rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Non-medical interventions to enhance return to work for people with cancer.The Cochrane database of systematic reviews · 2024
    Pooled it
  3. Trial
  4. Trial
  5. Review
  6. Article
  7. Recovering or working: women's experiences of working while coping with cancer: a qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

S J TammingaCoronel Institute of Occupational Health, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.
J H A M VerbeekCoronel Institute of Occupational Health, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.
M M E M BosDepartment of Internal Medicine, Reinier de Graaf Groep, Delft, The Netherlands.
G FonsDepartment of Gynaecology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
J J E M KitzenDepartment of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, The Netherlands.
P W PlaisierDepartment of Surgery, Albert Schweitzer Hospital, Dordrecht, The Netherlands.
M H W Frings-DresenCoronel Institute of Occupational Health, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.
A G E M de BoerCoronel Institute of Occupational Health, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands. a.g.deboer@amc.nl.ORCID 0000-0003-1942-6848
Albert Schweitzer Ziekenhuis · NLAmsterdam University Medical Centers · NLAmsterdam UMC Location University of Amsterdam · NLFinnish Institute of Occupational Health · FINetherlands Center for Occupational Diseases · NLReinier de Graaf Hospital · NL

Funding

European Cooperation in Science and Technology CANWON IS1211Instituut Gak ?Pathways to work? (www.verbeteronderzoek.nl)
6 · The paper itself

Abstract

Purpose Purpose is to: (1) study effectiveness of the hospital-based work support intervention for cancer patients at two years of follow-up compared to usual care and (2) identify which early factors predict time to return-to-work (RTW). Methods In this multi-center randomised controlled trial (RCT), 106 (self-)employed cancer patients were randomized to an intervention group or control group and provided 2 years of follow-up data. The intervention group received patient education and work-related support at the hospital. Primary outcome was RTW (rate and time) and quality of life (SF-36), and secondary outcomes were, work ability (WAI), and work functioning (WLQ). Univariate Cox regression analyses were performed to study which early factors predict time to full RTW. Results Participants were diagnosed with breast (61%), gynaecological cancer (35%), or other type of cancer (4%). RTW rates were 84% and 90% for intervention versus control group. They were high compared to national register-based studies. No differences between groups were found on any of the outcomes. Receiving chemotherapy (HR = 2.43, 95% CI 1.59-3.73 p < 0.001), low level of education (HR = 1.65, 95% CI 1.076-2.52 p = 0.02) and low work ability (HR = 1.09 [95% CI 1.04-1.17] p = 0.02) were associated with longer time to full RTW. Conclusions We found high RTW rates compared to national register-based studies and we found no differences between groups. Future studies should therefore focus on reaching the group at risk, which consist of patients who receive chemotherapy, have a low level of education and have a low work ability at diagnosis.

trial registrationNetherlands Trial Registry (NTR) (http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=1658): NTR1658.

Indexed as

AdultFemaleFollow-Up StudiesHumansMaleMiddle AgedNeoplasmsPhysical Functional PerformanceProgram EvaluationProportional Hazards ModelsQuality of LifeReturn to WorkTime FactorsHospitalNeoplasmsOncology serviceProgram effectivenessRandomized controlled trialReturn to work

Identifiers

PMID30778742
PMCPMC6838305
OpenAlexW2917717292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.