SynthesisArchives of orthopaedic and trauma surgery2019
The outcomes of total knee arthroplasty in morbidly obese patients: a systematic review of the literature.
Synthesis in Archives of orthopaedic and trauma surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04910048 (Impact of a Preoperative Patient Optimization Program on Preoperative Health, Eligibility, and Clinical & Patient-Reported Outcomes in Total Joint Arthroplasty), which is not on this map. Cited by 75 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of a Preoperative Patient Optimization Program on Preoperative Health, Eligibility, and Clinical & Patient-Reported Outcomes in Total Joint Arthroplasty
Who cites it
75 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Role of bariatric surgery in reducing periprosthetic joint infections in total knee arthroplasty. A systematic review and meta-analysis.BMC musculoskeletal disorders · 2024Pooled it
- The effect of obesity on revision rate in unicompartmental knee arthroplasty: a systematic review and meta-analysis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2021Pooled it
- App-based rehabilitation program after total knee arthroplasty: a randomized controlled trial.Archives of orthopaedic and trauma surgery · 2021Trial
- Higher body mass index is associated with larger postoperative improvement in patient-reported outcomes following total knee arthroplasty.BMC musculoskeletal disorders · 2021Trial
- Protocol for Novel Perioperative Optimization of Obese Osteoarthritic Patients pending Total Knee Replacement with glucagon-like peptide-1 receptor agonist (NPO-OOPS-TKR) : a pilot randomized controlled trial.Bone & joint open · 2026Article
- Mechanically aligned total knee arthroplasty demonstrates acceptable outcomes in obese patients, with insufficient evidence for alternative alignment strategies: A systematic review.Journal of experimental orthopaedics · 2026Review
- Metformin Use Is Associated With Reduced Inflammation and Pain After Total Knee Arthroplasty in Patients With Type 2 Diabetes.Orthopaedic surgery · 2026Article
- Preoperative Weight Loss Intervention With Glucagon-Like Peptides 1 Receptor Agonists Is Associated With Lower Complication Rates Following Primary Total Knee Arthroplasty Than Preoperative Bariatric Surgery.Arthroplasty today · 2026Article
- Elevated body mass index and clinical outcomes after surgical stabilization for shoulder instability: A systematic review.Journal of orthopaedics · 2026Review
- Article
- Frequency of deep vein thrombosis in patients undergoing total knee replacement using pneumatic tourniquet.Pakistan journal of medical sciences · 2026Article
- Recommendations of an international Delphi study group for total knee arthroplasty in obese patients.Archives of orthopaedic and trauma surgery · 2026Article
- SIMULTANEOUS CONTRALATERAL HIGH TIBIAL OSTEOTOMY DURING TOTAL KNEE ARTHROPLASTY: A NEW PERSPECTIVE IN ORTHOPEDIC SURGERY.Orthopedic reviews · 2026Article
- Article
- Is There a Body Mass Index Threshold for Patients Undergoing Primary Total Knee Replacement-A Literature Review.Journal of clinical medicine · 2025Review
- Knee Osteoarthritis: Current Insights Into Pathophysiology and Non-surgical Management Options.Cureus · 2025Review
- Review
- The Effect of Obesity on Simultaneous Bilateral Knee Arthroplasty Surgery.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- Influence of femoral component downsizing on knee extension and resultant extension gap in TKA.Journal of clinical orthopaedics and trauma · 2025Article
- Increased Body Mass Index is Associated With Increased Cost for Primary Total Knee Arthroplasty Exclusive of Readmissions and Complications.Arthroplasty today · 2025Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe increasing prevalence of obesity has led to an increase in total knee arthroplasties (TKAs) being undertaken in patients with a higher body mass index (BMI). TKA in morbidly obese patients can be technically challenging due to numerous anatomical factors and patient co-morbidities. The long-term outcomes in this patient group are unclear. This systematic review aims to compare the long-term revision rates, functional outcomes and complication rates of TKAs in morbidly obese versus non-obese patients.
methodsA search of PubMed, EMBASE and PubMed Central was conducted to identify studies that reported revision rates in a cohort of morbidly obese patients (BMI ≥ 40 kg/m
resultsNine studies were included in this review. There were 624 TKAs in morbidly obese patients and 9,449 TKAs in non-obese patients, average BMI values were 45.0 kg/m
conclusionsThis review suggests an increased mid to long-term revision rate following primary TKA in morbidly obese patients, however, these patients have a functional recovery which is comparable to non-obese individuals. There is also an increased risk of perioperative complications, such as superficial wound infection. Morbidly obese patients should be fully informed of these issues prior to undergoing primary TKA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.