Evidence map›Paper›PMID 30778668›Full record

Observational studyClinical research in cardiology : official journal of the German Cardiac Society2019

Relation of lowering door-to-balloon time and mortality in ST segment elevation myocardial infarction patients undergoing percutaneous coronary intervention.

David Zahler, Keren Lee-Rozenfeld, Dor Ravid, Zach Rozenbaum, Shmuel Banai, Gad Keren, Yacov Shacham

Erratum issuedAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Clinical research in cardiology : official journal of the German Cardiac Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Article
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  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Observational
  10. COVID-19 sends STEMI to quarantine!?Clinical research in cardiology : official journal of the German Cardiac Society · 2020
    Article
  11. Disparities of demographics, clinical characteristics, and hospital outcomes of AMI pilgrims vs non-pilgrims-tertiary center experience.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2020
    Article
  12. Predictors of transportation delay in patients with suspected ST-elevation-myocardial infarction in the VIENNA-STEMI network.Clinical research in cardiology : official journal of the German Cardiac Society · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

David ZahlerDivision of Cardiovascular Diseases and Internal Medicine, Department of Cardiology, Tel-Aviv Sourasky Medical Center affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizmann Street, Tel-Aviv, Israel. David.zahler@gmail.com.ORCID http://orcid.org/0000-0002-6887-3348
Keren Lee-RozenfeldDivision of Cardiovascular Diseases and Internal Medicine, Department of Cardiology, Tel-Aviv Sourasky Medical Center affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizmann Street, Tel-Aviv, Israel.
Dor RavidDivision of Cardiovascular Diseases and Internal Medicine, Department of Cardiology, Tel-Aviv Sourasky Medical Center affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizmann Street, Tel-Aviv, Israel.
Zach RozenbaumDivision of Cardiovascular Diseases and Internal Medicine, Department of Cardiology, Tel-Aviv Sourasky Medical Center affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizmann Street, Tel-Aviv, Israel.
Shmuel BanaiDivision of Cardiovascular Diseases and Internal Medicine, Department of Cardiology, Tel-Aviv Sourasky Medical Center affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizmann Street, Tel-Aviv, Israel.
Gad KerenDivision of Cardiovascular Diseases and Internal Medicine, Department of Cardiology, Tel-Aviv Sourasky Medical Center affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizmann Street, Tel-Aviv, Israel.
Yacov ShachamDivision of Cardiovascular Diseases and Internal Medicine, Department of Cardiology, Tel-Aviv Sourasky Medical Center affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizmann Street, Tel-Aviv, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrent guidelines for the treatment of ST-segment elevation myocardial infarction (STEMI) recommend a door-to-balloon time (DBT) of ≤ 90 min for patients undergoing primary percutaneous coronary intervention (PCI). We aimed to investigate the possible impact of further reduction in DBT intervals beyond the 90 min cutoff on short and long-term outcomes among STEMI patients undergoing primary PCI.

methodsWe retrospectively studied 889 STEMI patients (median age 61 years, 83% men) who underwent successful primary PCI and had a DBT of ≤ 90 min. Patients were stratified according to DBT into 2 groups: < 60 min and 60-90 min. Patients records were assessed for the occurrence of in-hospital complications, 30-day and 1-year mortality.

resultsPatients having DBT < 60 min (n = 608, 68%) were more likely to present earlier, in daytime and weekdays, and had better post-procedural left ventricular ejection fraction and lower 30-day mortality (3% vs. 6%, p = 0.03). Mortality over 1-year was significantly lower among patients having DBT < 60 compared to DBT of 60-90 min (4.6% vs. 9.6%, p = 0.004). In a binary logistic regression model DBT < 60 min was associated with 51% risk reduction for 1-year mortality (OR 0.49, 95% CI 0.25-0.93, p = 0.03).

conclusionsAmong STEMI patients undergoing primary PCI within 90 min of admission DBT < 60 min was independently associated with better 1-year mortality.

Indexed as

AdultAgedAngioplasty, Balloon, CoronaryFemaleHumansMaleMiddle AgedPercutaneous Coronary InterventionRetrospective StudiesST Elevation Myocardial InfarctionTime FactorsTime-to-TreatmentTreatment OutcomeCardiac intensive care unitDoor-to-balloon timePrimary percutaneous coronary interventionST-segment elevation myocardial infarction

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.