ReviewApplied microbiology and biotechnology2019
Occurrence, function, and biosynthesis of mycofactocin.
Review in Applied microbiology and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed.
- A Versatile Enzymatic Pathway for Modification of Peptide C‑Termini.ACS central science · 2025Article
- Genome mining and metabolite profiling illuminate the taxonomy status and the cytotoxic activity of a mangrove-derived Microbacterium alkaliflavum sp. nov.BMC microbiology · 2025Article
- MftG is crucial for ethanol metabolism of mycobacteria by linking mycofactocin oxidation to respiration.eLife · 2025Article
- Fitness and adaptive evolution of a Rhodococcus sp. harboring dioxin-catabolic plasmids.World journal of microbiology & biotechnology · 2025Article
- A mycofactocin-associated dehydrogenase is essential for ethylene glycol metabolism by Rhodococcus jostii RHA1.Applied microbiology and biotechnology · 2024Article
- The catabolism of ethylene glycol byApplied and environmental microbiology · 2024Article
- Novel aspects of ethylene glycol catabolism.Applied microbiology and biotechnology · 2024Review
- BGCFlow: systematic pangenome workflow for the analysis of biosynthetic gene clusters across large genomic datasets.Nucleic acids research · 2024Article
- Nocardioides jiangxiensis sp. nov., a novel actinobacterium isolated from lakeside soil, exhibiting the biosynthesis potential of mycofactocin.Antonie van Leeuwenhoek · 2024Article
- Mechanistic insights into sulfur source-driven physiological responses and metabolic reorganization in the fuel-biodesulfurizingApplied and environmental microbiology · 2023Article
- Article
- Mechanism of Action of Ribosomally Synthesized and Post-Translationally Modified Peptides.Chemical reviews · 2022Review
- Nitric Oxide-Dependent Electron Transport Chain Inhibition by the CytochromeAntimicrobial agents and chemotherapy · 2021Article
- Biogenesis of the peptide-derived redox cofactor pyrroloquinoline quinone.Current opinion in chemical biology · 2020Review
- Matters of class: coming of age of class III and IV lanthipeptides.RSC chemical biology · 2020Review
- Structure elucidation of the redox cofactor mycofactocin reveals oligo-glycosylation by MftF.Chemical science · 2020Article
- The manifold roles of microbial ribosomal peptide-based natural products in physiology and ecology.The Journal of biological chemistry · 2020Review
- Impact of Oxygen Supply and Scale Up onFrontiers in bioengineering and biotechnology · 2020Article
- Genome mining strategies for ribosomally synthesised and post-translationally modified peptides.Computational and structural biotechnology journal · 2020Review
- MftD Catalyzes the Formation of a Biologically Active Redox Center in the Biosynthesis of the Ribosomally Synthesized and Post-translationally Modified Redox Cofactor Mycofactocin.Journal of the American Chemical Society · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Mycofactocin is a member of the rapidly growing class of ribosomally synthesized and post-translationally modified peptide (RiPP) natural products. Although the mycofactocin biosynthetic pathway is widely distributed among Mycobacterial species, the structure, function, and biosynthesis of the pathway product remain unknown. This mini-review will discuss the current state of knowledge regarding the mycofactocin biosynthetic pathway. In particular, we focus on the architecture and distribution of the mycofactocin biosynthetic cluster, mftABCDEF, among the Actinobacteria phylum. We discuss the potential molecular and physiological role of mycofactocin. We review known biosynthetic steps involving MftA, MftB, MftC, and MftE and relate them to pyrroloquinoline quinone biosynthesis. Lastly, we propose the function of the remaining putative biosynthetic enzymes, MftD and MftF.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.