ArticleNeuroradiology2019
Risk factors of intracranial hemorrhage after mechanical thrombectomy of anterior circulation ischemic stroke.
Article in Neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
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Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 78 citations in OpenAlex.
- Asymptomatic Intracerebral Hemorrhage Following Endovascular Stroke Therapy Is Not Benign: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2024Pooled it
- Risk factors of hemorrhagic transformation in acute ischaemic stroke: A systematic review and meta-analysis.Frontiers in neurology · 2023Pooled it
- Trial
- Association between CT Perfusion Parameters and Hemorrhagic Transformation after Endovascular Treatment in Acute Ischemic Stroke: Results from the ESCAPE-NA1 Trial.AJNR. American journal of neuroradiology · 2024Trial
- Trial
- Increased intracranial hemorrhage of mechanical thrombectomy in acute ischemic stroke patients with atrial fibrillation.Journal of thrombosis and thrombolysis · 2021Trial
- Clinical Significance of Asymptomatic Intracranial Hemorrhage Following Thrombectomy for Large-Vessel Occlusion: Insight from the ANGEL-ACT Registry.Clinical neuroradiology · 2026Article
- Predictors of acute post-thrombectomy intracranial hemorrhage expansion in anterior circulation infarcts.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026Article
- Plasma D-dimer can predict malignant brain edema after thrombectomy in noncardioembolic acute cerebral infarction.BMC neurology · 2026Article
- Association Between Direct Oral Anticoagulants and the Risk of Internal Carotid Artery Occlusion in Patients Eligible for Thrombectomy.Clinical neuroradiology · 2026Observational
- Intracranial haemorrhage without early clinical deterioration after mechanical thrombectomy: rethinking the "asymptomatic" label.European stroke journal · 2026Observational
- Risk of Symptomatic Intracranial Hemorrhage After Mechanical Thrombectomy in Randomized Clinical Trials: A Systematic Review and Meta-Analysis.Brain sciences · 2025Review
- Combinations of Clinical Factors, CT Signs, and Radiomics for Differentiating High-Density Areas after Mechanical Thrombectomy in Patients with Acute Ischemic Stroke.AJNR. American journal of neuroradiology · 2025Article
- Intracranial hemorrhage prediction in acute ischemic stroke patients with anterior circulation tandem lesions following endovascular thrombectomy.Frontiers in neurology · 2025Article
- Incidence of intracranial hemorrhagic complications after anterior circulation endovascular thrombectomy in relation to occlusion site: a nationwide observational register study.Journal of neurointerventional surgery · 2024Observational
- A clinical and computed tomography-based nomogram to predict the outcome in patients with anterior circulation large vessel occlusion after endovascular mechanical thrombectomy.Japanese journal of radiology · 2024Article
- Post-endovascular treatment, blood-brain barrier disruption, predicts patient outcomes better than pre-treatment status.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- The impact of blood pressure variability on the development of parenchymal hematoma in acute cerebral infarction with atrial fibrillation.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Discrimination of Hemorrhage and Contrast Media in a Head Phantom on Photon-Counting Detector CT Data.AJNR. American journal of neuroradiology · 2024Article
- Blood glucose to predict symptomatic intracranial hemorrhage after endovascular treatment of acute ischemic stroke with large infarct core: a prospective observational study.Frontiers in neurology · 2024Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIntracranial hemorrhage (ICH) is a potentially severe complication after mechanical thrombectomy (MT). Here, we investigated risk factors for the occurrence of any and symptomatic ICH after MT due to large-vessel occlusion of the anterior circulation.
methodsConsecutive patients with acute ischemic anterior circulation stroke with large-vessel occlusion undergoing MT were analyzed. ICH was categorized according to the Heidelberg Bleeding Classification. Forty-three procedural and clinical parameters were analyzed using univariate tests and multivariate logistic regressions.
resultsOf 612 patients, any ICH was detected in 195 (31.9%), while 27 (4.4%) developed a symptomatic ICH. Infarct size > 1/3 of vascular territory in control imaging (OR 2.18, 95% CI 1.45-3.21), higher serum glucose levels (OR 1.23 for change of 15 units mg/dL, 95% CI 1.10-1.39), and higher thrombectomy maneuver count (OR 1.21, 95% CI 1.11-1.32) were significantly associated with a higher risk of developing any ICH compared to no ICH. Wake-up strokes (OR 3.99, 95% CI 1.38-11.60), transfer from an external clinic (OR 3.04, 95% CI 1.24-7.48), and higher serum glucose levels (OR 1.22 for change of 15 units mg/dL, 95% CI 1.05-1.42) were revealed as independent risk factors for development of symptomatic ICH compared to no symptomatic ICH. Patients with no infarct demarcation (OR 0.10, 95% CI 0.01-0.80) and complete recanalization (OR 0.57, 95% CI 0.37-0.86) showed a lower risk of developing any ICH.
conclusionWake-up strokes and patients who are treated within a drip-and-ship concept are especially vulnerable for symptomatic ICH, while complete recanalization, contrary to subtotal recanalization only, was revealed as a protective factor against ICH.
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