Evidence map›Paper›PMID 30778086›Full record

SynthesisNPJ primary care respiratory medicine2019

The role of oral magnesium supplements for the management of stable bronchial asthma: a systematic review and meta-analysis.

Faisal Abuabat, Abdulaziz AlAlwan, Emad Masuadi, Mohammad Hassan Murad, Hamdan Al Jahdali, Mazen Saleh Ferwana

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in NPJ primary care respiratory medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Magnesium: Hype and Health Benefits.Current nutrition reports · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. MgClBiological trace element research · 2023
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Faisal AbuabatFamily Medicine Residency Program, King Abdulaziz Medical City, National Guard Health Affairs, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Abdulaziz AlAlwanFamily Medicine Residency Program, King Abdulaziz Medical City, National Guard Health Affairs, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Emad MasuadiDepartment of Medical Education, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi Arabia.
Mohammad Hassan MuradEvidence-Based Practice Center, Mayo Clinic, Rochester, Minnesota, USA.
Hamdan Al JahdaliKing Saud bin Abdulaziz University for Health Sciences, King Adulaziz Medical City, National Guard Health Affairs, King Abdullah International Medical Research Center, Riyadh, 11665, Saudi Arabia.
Mazen Saleh FerwanaKing Saud bin Abdul-Aziz University for Health Sciences; National & Gulf Center for Evidence Based Health Practice, King Abdullah International Medical Research Center, Family Medicine & Primary Healthcare Department, King Abdul-Aziz Medical City, Ministry of National Guard - Health Affairs, Riyadh, Saudi Arabia. ferwanam@ngha.med.sa.
National Guard Health Affairs · SAKing Abdullah International Medical Research Center · SAKing Saud bin Abdulaziz University for Health Sciences · SAMayo Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma is a chronic lung disease characterized by airway inflammation and hyper-responsiveness of airway smooth muscles. There is growing evidence that magnesium may have a role in managing asthma through its dual effect as an anti-inflammatory and bronchodilating agent. To assess the efficacy of oral magnesium supplements in chronic asthmatic patients. In addition to searching through Clinicaltrials.gov/ and references for oral magnesium supplement studies, we performed a database search in Medline, CINAHL, CENTRAL, and Embase. We contacted the authors of the included trials to ask for additional information. We included randomized controlled trials that compared oral magnesium supplements versus placebo, in addition to standard asthma treatment in mild-moderate asthmatic adults and children (older than 6 years). Two reviewers independently performed the study selection, data abstraction, and the assessment of the risk of bias. Eight trials at moderate risk of bias enrolling a total of 917 patients were included. Oral magnesium improved FEV1 at week 8 (5.69 (L/min); 95% CI: 1.92, 9.46; I

Indexed as

Dietary SupplementsAdministration, OralAsthmaBronchodilator AgentsHumansMagnesiumBronchodilator AgentsMagnesium

Identifiers

PMID30778086
PMCPMC6379356
OpenAlexW2912320119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.