ArticleNature communications2019
Underpinning heterogeneity in synaptic transmission by presynaptic ensembles of distinct morphological modules.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 74 citations in OpenAlex.
- Formation, Organization, and Maintenance of Synaptic Vesicle Pools: From Molecules to Structure and Dynamics.Advances in neurobiology · 2026Review
- Synaptic input variation enhances rate coding at the expense of temporal precision in cochlear nucleus neurons.PLoS biology · 2026Article
- Input-Specific Organization of Intrinsic Excitability Expands Coding Capacity of Fast-Spiking Auditory Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Intersectin-1 enhances calcium-dependent replenishment of the readily releasable pool of synaptic vesicles during development.The Journal of physiology · 2025Article
- Number and relative abundance of synaptic vesicles in functionally distinct priming states determine synaptic strength and short-term plasticity.The Journal of physiology · 2025Article
- Cellular and synaptic specializations for sub-millisecond precision in the mammalian auditory brainstem.Frontiers in cellular neuroscience · 2025Review
- Article
- CaeLife · 2024Article
- CabioRxiv : the preprint server for biology · 2024Article
- Different states of synaptic vesicle priming explain target cell type-dependent differences in neurotransmitter release.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Optical measurement of glutamate release robustly reports short-term plasticity at a fast central synapse.Frontiers in molecular neuroscience · 2024Article
- Article
- Tau target identification reveals NSF-dependent effects on AMPA receptor trafficking and memory formation.The EMBO journal · 2022Article
- Time Course of Activity-Dependent Changes in Auditory Nerve Synapses Reveals Multiple Underlying Cellular Mechanisms.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Determinants of synapse diversity revealed by super-resolution quantal transmission and active zone imaging.Nature communications · 2022Article
- Article
- Using ephaptic coupling to estimate the synaptic cleft resistivity of the calyx of Held synapse.PLoS computational biology · 2021Article
- The glutamatergic synapse: a complex machinery for information processing.Cognitive neurodynamics · 2021Review
- Ultrastructural maturation of the endbulb of Held active zones comparing wild-type and otoferlin-deficient mice.iScience · 2021Article
- Presynaptic voltage-gated calcium channels in the auditory brainstem.Molecular and cellular neurosciences · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synaptic heterogeneity is widely observed but its underpinnings remain elusive. We addressed this issue using mature calyx of Held synapses whose numbers of bouton-like swellings on stalks of the nerve terminals inversely correlate with release probability (Pr). We examined presynaptic Ca
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.