ArticleNature communications2019
The apocarotenoid metabolite zaxinone regulates growth and strigolactone biosynthesis in rice.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.
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85 citing papers in PubMed, 181 citations in OpenAlex.
- Comprehensive analysis of the effects of foliar application of the synthetic strigolactone analog GR24 during the growth period on postharvest quality and metabolic indicators of pak choi.Food chemistry: X · 2026Article
- Arbuscular mycorrhizal symbiosis in tomato roots with a diverse range of carotene accumulation.Mycorrhiza · 2026Article
- Zaxinone mimics boost growth and productivity of wheat under normal and low-nutrient regimes.BMC plant biology · 2026Article
- Catalytic mechanism for β-carotene isomerisation and substrate selectivity by the strigolactone biosynthetic enzymes D27 and D27like1.Scientific reports · 2026Article
- An evolutionarily diverged CCD4 enzyme negatively regulates mesocotyl elongation in rice.The New phytologist · 2026Article
- Regulation of apocarotenoids for quality improvement and biofortification of horticultural crops.Journal of advanced research · 2026Review
- Genome-Wide Analysis of TomatoPlants (Basel, Switzerland) · 2026Article
- Evolutionary adaptation of CCD4 enzymes inFrontiers in plant science · 2026Article
- LC-MS Analysis and Quantification of Plants Apocarotenoids.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Carotenoid biosynthesis drives root plasticity through aerenchyma and iron plaque formation in rice.Nature plants · 2026Article
- Molecular Basis for Catalysis and Regulation of the Strigolactone Catabolic Enzyme CXE15.Nature communications · 2025Article
- LYCOPENE β-CYCLASE overexpression improves growth, modulates hormone content, and affects rhizospheric interactions in tobacco and tomato roots.Plant cell reports · 2025Article
- Field resistance to Orobanche crenata in pea (Pisum sativum L.): beyond strigolactones.BMC plant biology · 2025Article
- The metabolic landscape of tomato roots during arbuscular mycorrhizal symbiosis reveals lipid-related metabolic rewiring.Plant cell reports · 2025Article
- Arabidopsis response to the apocarotenoid zaxinone involves interference with strigolactone signaling via binding to DWARF14.Nature communications · 2025Article
- Disruption of the karrikin receptor DWARF 14 LIKE (D14L) gene leads to distinct effects on root and shoot growth, and reprogramming of central metabolism in rice.Journal of experimental botany · 2025Article
- Genome-wide identification of CCD gene family in Peach (Prunus persica L. Batsch) and expression analysis with aroma norisoprenoids.BMC plant biology · 2025Article
- Montbretia flowers as a source of bioactive crocins: Biotechnology tools and delivery systems.Biotechnology reports (Amsterdam, Netherlands) · 2025Article
- Genome-wide identification and gene expression pattern analysis of the carotenoid cleavage oxygenase gene family in Fagopyrum tataricum.BMC plant biology · 2025Article
- Zaxinone Synthase overexpression modulates rice physiology and metabolism, enhancing nutrient uptake, growth and productivity.Plant, cell & environment · 2025Article
25 more citing papers are in PubMed but not listed here.
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Authors and funding
19 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carotenoid cleavage dioxygenases (CCDs) form hormones and signaling molecules. Here we show that a member of an overlooked plant CCD subfamily from rice, that we name Zaxinone Synthase (ZAS), can produce zaxinone, a novel apocarotenoid metabolite in vitro. Loss-of-function mutants (zas) contain less zaxinone, exhibit retarded growth and showed elevated levels of strigolactones (SLs), a hormone that determines plant architecture, mediates mycorrhization and facilitates infestation by root parasitic weeds, such as Striga spp. Application of zaxinone can rescue zas phenotypes, decrease SL content and release and promote root growth in wild-type seedlings. In conclusion, we show that zaxinone is a key regulator of rice development and biotic interactions and has potential for increasing crop growth and combating Striga, a severe threat to global food security.
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