Evidence map›Paper›PMID 30777857›Full record

ArticleCancer prevention research (Philadelphia, Pa.)2019

Rafael Guerrero-Preston, Fahcina Lawson, Sebastian Rodriguez-Torres, Maartje G Noordhuis, Francesca Pirini, Laura Manuel, Blanca L Valle, Tal Hadar, Bianca Rivera, Oluwasina Folawiyo and 7 more

Erratum issuedOpen access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer prevention research (Philadelphia, Pa.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Breast Cancer Disparities and the Impact of Geography.Surgical oncology clinics of North America · 2022
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 5 countries.

Rafael Guerrero-PrestonDepartment of Otolaryngology and Head and Neck Surgery, Johns Hopkins University, School of Medicine, Baltimore, Maryland. rafael.guerrero@upr.edu.
Fahcina LawsonDepartment of Otolaryngology and Head and Neck Surgery, Johns Hopkins University, School of Medicine, Baltimore, Maryland.
Sebastian Rodriguez-TorresDepartment of Otolaryngology and Head and Neck Surgery, Johns Hopkins University, School of Medicine, Baltimore, Maryland.ORCID 0000-0003-1264-0497
Maartje G NoordhuisDepartment of Otolaryngology and Head and Neck Surgery, Johns Hopkins University, School of Medicine, Baltimore, Maryland.
Francesca PiriniBiosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy.
Laura ManuelDepartment of Epidemiology and Biostatistics, The University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Blanca L ValleDepartment of Otolaryngology and Head and Neck Surgery, Johns Hopkins University, School of Medicine, Baltimore, Maryland.
Tal HadarBreast Health Unit, Department of General Surgery, Shaare Zedek Medical Center, Jerusalem, Israel.
Bianca RiveraDepartment of Otolaryngology, University of Puerto Rico, School of Medicine, San Juan, Puerto Rico.
Oluwasina FolawiyoDepartment of Otolaryngology and Head and Neck Surgery, Johns Hopkins University, School of Medicine, Baltimore, Maryland.
Adriana BaezDepartment of Otolaryngology, University of Puerto Rico, School of Medicine, San Juan, Puerto Rico.
Luigi MarchionniDepartment of Oncology, Johns Hopkins University, School of Medicine, Baltimore, Maryland.ORCID 0000-0002-7336-8071
Wayne M KochDepartment of Otolaryngology and Head and Neck Surgery, Johns Hopkins University, School of Medicine, Baltimore, Maryland.
William H WestraDepartment of Pathology, The Icahn School of Medicine at Mount Sinai Hospital, New York, New York.
Young J KimDepartment of Otolaryngology, Vanderbilt University School of Medicine, Nashville, Tennessee.ORCID 0000-0001-8434-4561
James R EshlemanDepartment of Pathology, Johns Hopkins University, School of Medicine, Baltimore, Maryland.
David SidranskyDepartment of Otolaryngology and Head and Neck Surgery, Johns Hopkins University, School of Medicine, Baltimore, Maryland.
Johns Hopkins University · USUniversity of Puerto Rico System · PRHarvard University · USIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori · ITMount Sinai Hospital · USShaare Zedek Medical Center · ILThe University of Texas Health Science Center at San Antonio · USUniversity Medical Center Groningen · NLVanderbilt University · US

Funding

INTEGRATED DEVELOPMENT OF NOVEL MOLECULAR MARKERSU01CA084986 · NCI · JOHNS HOPKINS UNIVERSITY · PI SIDRANSKY, DAVID · 1999 to 2014
$33.8M
TUMOR SUPPRESOR GENE PROMOTER HYPERMETHYLATION FOR DETECTION OF HEAD AND NECKP50DE019032 · NIDCR · JOHNS HOPKINS UNIVERSITY · PI BORRELLO, IVAN M. · 2007 to 2016
$27.1M
Bronx-Einstein Training in Teaching and Research (BETTR), an IRACDA programK12GM102779 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Dianne Cox, Johanna Patricia Daily · 2012 to 2026
$9.2M
Large-Scale Genetic Analyses of Human CancerR01CA121113 · NCI · JOHNS HOPKINS UNIVERSITY · PI ANAGNOSTOU, VALSAMO, VELCULESCU, VICTOR E. · 2006 to 2022
$4.3M
Genone-wide Discovery of Molecular Alterations in Head and Neck CancerRC2DE020957 · NIDCR · JOHNS HOPKINS UNIVERSITY · PI AGRAWAL, NISHANT, SIDRANSKY, DAVID · 2009 to 2010
$2.5M
Epigenomic Markers of HNSCC Survival Across Ethnic GroupsK01CA164092 · NCI · JOHNS HOPKINS UNIVERSITY · PI GUERRERO-PRESTON, RAFAEL · 2011 to 2014
$530k
NCI NIH HHS K01 CA164092NCI NIH HHS R01 CA121113NCI NIH HHS U01 CA084986NIDCR NIH HHS P50 DE019032NIDCR NIH HHS RC2 DE020957NIGMS NIH HHS K12 GM102779
6 · The paper itself

Abstract

To inform novel personalized medicine approaches for race and socioeconomic disparities in head and neck cancer, we examined germline and somatic mutations, immune signatures, and epigenetic alterations linked to neighborhood determinants of health in Black and non-Latino White (NLW) patients with head and neck cancer. Cox proportional hazards revealed that Black patients with squamous cell carcinoma of head and neck (HNSCC) with

Indexed as

DNA MethylationGerm-Line MutationHealth Status DisparitiesSocial Determinants of HealthAdultBiomarkers, TumorBlack or African AmericanCase-Control StudiesFemaleFollow-Up StudiesGene Expression Regulation, NeoplasticHead and Neck NeoplasmsHumansJanus Kinase 3Lymphocytes, Tumor-InfiltratingMaleBiomarkers, TumorJAK3 protein, humanJanus Kinase 3TP53 protein, humanTumor Suppressor Protein p53

Identifiers

PMID30777857
PMCPMC6800037
OpenAlexW2915293386

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.