Evidence map›Paper›PMID 30777332›Full record

ArticleBiochemical and biophysical research communications2019

Prognostic significance of high metabolic activity in breast cancer: PET signature in breast cancer.

Sanghee Kang, Eui Hyun Kim, Jun-Eul Hwang, Ji-Hyun Shin, Yun Seong Jeong, Sun Young Yim, Eun Wook Joo, Young Gyu Eun, Dong Jin Lee, Bo Hwa Sohn and 3 more

Open access · greenAbstract read
In one paragraph

Article in Biochemical and biophysical research communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Prognostic Prediction of BRCA Mutations byMolecular imaging and radionuclide therapy · 2021
    Article
  6. Conventional Nanosized Drug Delivery Systems for Cancer Applications.Advances in experimental medicine and biology · 2021
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Sanghee KangDepartment of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Surgery, Korea University College of Medicine, Seoul, Republic of Korea.
Eui Hyun KimDepartment of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Neurosurgery, Severance Hospital, Brain Tumor Center, Yonsei University College of Medicine, Seoul, Republic of Korea.
Jun-Eul HwangDepartment of Hematology-Oncolgy, Chonnam National University Medical School, Gwangju, Republic of Korea.
Ji-Hyun ShinDepartment of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Yun Seong JeongDepartment of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Sun Young YimDepartment of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Republic of Korea.
Eun Wook JooDepartment of Gynecology, School of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Young Gyu EunDepartment of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Dong Jin LeeDepartment of Otolaryngology-Head and Neck Surgery, School of Medicine, Hallym University, Seoul, Republic of Korea.
Bo Hwa SohnDepartment of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Sung Hwan LeeDepartment of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Bora LimDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Ju-Seog LeeDepartment of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: jlee@mdanderson.org.
The University of Texas MD Anderson Cancer Center · USKyung Hee University · KRChonnam National University · KRHallym University · KR

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
DEVELOPMENT AND VALIDATION OF PROGNOSTIC MODEL FOR GASTRIC CANCERR01CA150229 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LEE, JU-SEOG · 2010 to 2013
$1.1M
NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA150229
6 · The paper itself

Abstract

High metabolic activity, reflected in increased glucose uptake, is one of the hallmarks of many cancers including breast cancer. However, not all cancers avidly take up glucose, suggesting heterogeneity in their metabolic demand. Thus, we aim to generate a genomic signature of glucose hypermetabolism in breast cancer and examine its clinical relevance. To identify genes significantly associated with glucose uptake, gene expression data were analyzed together with the standardized uptake values (SUVmax) of

Indexed as

Breast NeoplasmsFemaleFluorodeoxyglucose F18Gene Expression Regulation, NeoplasticGlucoseGlycolysisHumansPositron-Emission TomographyPrognosisFluorodeoxyglucose F18Glucose(18)F-fluorodeoxy-glucoseBreast cancerMYCPositron emission tomographyTBX2

Identifiers

PMID30777332
PMCPMC8356554
OpenAlexW2914002249

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.