ArticleThe American journal of cardiology2019
Cardiovascular Outcomes of Patients With Pulmonary Hypertension Undergoing Noncardiac Surgery.
Article in The American journal of cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 81 citations in OpenAlex.
- Inhaled pulmonary vasodilators in pulmonary hypertension: Perioperative use and clinical considerations.JHLT open · 2026Article
- Echocardiography Does Not Delay Surgery in Elderly Patients with Hip Fractures, and Pulmonary Hypertension and Decreased Left Ventricular Ejection Fraction Are Associated with In-Hospital Mortality.Journal of clinical medicine · 2026Article
- Article
- Incidence of Adverse Cardiac Events After Liver Transplantation in Patients With Different Hemodynamic Classifications of Pulmonary Hypertension.International journal of hepatology · 2026Article
- Pressure-flow discordance in perioperative pulmonary hypertension: a mechanism-based review and provisional five-domain right-heart model for noncardiac surgery.Frontiers in medicine · 2026Review
- Noncardiac surgery for severe pulmonary hypertension: two surgeries in one patient and a review of the literature.Annals of medicine and surgery (2012) · 2025Article
- Elevated right ventricular systolic pressure and outcomes after emergency hip surgery: a case control study.BMC anesthesiology · 2025Article
- Preoperative echocardiography and anesthetic drugs as predictors of post-induction hypotension during general anesthesia: a prospective observational study.Scientific reports · 2024Observational
- Management of pulmonary hypertension in special conditions.The European respiratory journal · 2024Review
- Epidemiology of perioperative RV dysfunction: risk factors, incidence, and clinical implications.Perioperative medicine (London, England) · 2024Review
- Arrhythmias in Patients with Pulmonary Hypertension and Right Ventricular Failure: Importance of Rhythm Control Strategies.Journal of clinical medicine · 2024Review
- Should All Patients With Pulmonary Hypertension Undergoing Non-Cardiac Surgery Be Managed by Cardiothoracic Fellowship-Trained Anesthesiologists?Seminars in cardiothoracic and vascular anesthesia · 2023Article
- Perioperative Complications in Patients with Systemic Sclerosis: A Comparative Cohort Analysis.Medical research archives · 2023Article
- Article
- Unrecognized Pulmonary Hypertension in Non-Cardiac Surgical Patients: At-Risk Populations, Preoperative Evaluation, Intraoperative Management and Postoperative Complications.Journal of cardiovascular development and disease · 2023Review
- Association between intraoperative pulmonary artery pressure and cardiovascular complications after off-pump coronary artery bypass surgery: a single-center observational study.BMC anesthesiology · 2023Observational
- Article
- Perioperative cardiovascular pathophysiology in patients undergoing lung resection surgery: a narrative review.British journal of anaesthesia · 2023Review
- Article
- Monitored anesthesia care for craniotomy in a patient with Eisenmenger syndrome: A case report.World journal of clinical cases · 2022Article
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Authors and funding
5 authors at 3 institutions in 1 country.
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Abstract
Pulmonary hypertension (PH), defined by a mean pulmonary artery pressure of >25mm Hg at rest, is strongly associated with morbidity and mortality in the perioperative period. The prevalence and outcomes of PH among patients referred for major noncardiac surgery in the United States are unknown. Patients ≥18 years of age hospitalized for noncardiac surgery were identified from Healthcare Cost and Utilization Project's National Inpatient Sample data from 2004 to 2014. Pulmonary hypertension was defined by International Classification of Diseases, Ninth Revision diagnosis codes. The primary outcome was perioperative major adverse cardiovascular events (MACCE), defined as in-hospital death, myocardial infarction, or ischemic stroke. Among 17,853,194 hospitalizations for major noncardiac surgery, 143,846 (0.81%) had PH. MACCE occurred in 8.3% of hospitalizations with any diagnosis of PH in comparison to 2.0% of those without PH (p <0.001), driven by an increased frequency of death (4.4% vs 1.1%, p <0.001) and nonfatal myocardial infarction (3.2% vs 0.6%, p <0.001). After adjusting for demographics, clinical covariates, and surgery type, PH remained independently associated with MACCE (aOR 1.43, 95% CI 1.40 to 1.46). In conclusion, PH is associated with perioperative major adverse cardiovascular events. Careful patient selection, recognition of perioperative risks, and appropriate intraoperative hemodynamic monitoring may improve perioperative cardiovascular outcomes.
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