ArticleeLife2019
Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification.
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Chaperonin in health and disease.Molecular biomedicine · 2026Review
- frizzled 5 mutant zebrafish are genetically sensitised to developing microphthalmia and coloboma.Disease models & mechanisms · 2025Article
- Characterization of an eye field-like state during optic vesicle organoid development.Development (Cambridge, England) · 2023Article
- Review
- Cell fate decisions, transcription factors and signaling during early retinal development.Progress in retinal and eye research · 2022Review
- Allele-specific gene expression can underlie altered transcript abundance in zebrafish mutants.eLife · 2022Article
- Eye morphogenesis in the blind Mexican cavefish.Biology open · 2021Article
- Article
- Xenopus embryos show a compensatory response following perturbation of the Notch signaling pathway.Developmental biology · 2020Article
- Tissue-Specific Requirement for the GINS Complex During Zebrafish Development.Frontiers in cell and developmental biology · 2020Article
- Developmentally regulatedeLife · 2019Article
- De Novo Missense Variants in FBXW11 Cause Diverse Developmental Phenotypes Including Brain, Eye, and Digit Anomalies.American journal of human genetics · 2019Article
- Looking to the future of zebrafish as a model to understand the genetic basis of eye disease.Human genetics · 2019Review
Corrections and comments
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Authors and funding
19 authors.
Funding
Abstract
The vertebrate eye originates from the eye field, a domain of cells specified by a small number of transcription factors. In this study, we show that Tcf7l1a is one such transcription factor that acts cell-autonomously to specify the eye field in zebrafish. Despite the much-reduced eye field in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.