ArticleBMC oral health2019
Risk factors of early childhood caries (ECC) among children in Beijing - a prospective cohort study.
Article in BMC oral health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Is Mutans Streptococci count a risk predictor of Early Childhood Caries? A systematic review and meta-analysis.BMC oral health · 2023Pooled it
- Strain-level genomic variation ofPeerJ · 2026Article
- Development and evaluation of an early childhood caries prediction model: a deep learning-based hybrid statistical modelling approach.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Article
- Bibliometric Analysis of Cross-Sectional Studies on Early Childhood Caries.Healthcare (Basel, Switzerland) · 2025Article
- Mothers' Knowledge, Attitude, and Behavior Concerning Their Kindergarten Children's Oral Health: A Cross-Sectional Study.Clinical and experimental dental research · 2025Article
- Risk Factors Associated with Children's Behavior in Dental Clinics: A Cross-Sectional Study.Children (Basel, Switzerland) · 2024Article
- Risk Factors of Early Childhood Caries among Preschool Children in Madipakkam, Chennai: Cross-Sectional Survey.Journal of pharmacy & bioallied sciences · 2024Article
- A Prospective Longitudinal Study of Early Childhood Caries Onset in Initially Caries-Free Children.JDR clinical and translational research · 2023Article
- OXIS Contacts and Approximal Caries in Preschool Children: A Prospective Cohort Study.Caries research · 2023Article
- Evaluation of Children Caries Risk Factors: A Narrative Review of Nutritional Aspects, Oral Hygiene Habits, and Bacterial Alterations.Children (Basel, Switzerland) · 2022Review
- Analysis of salivary proteomic biomarkers for the surveillance of changes in high-risk status of early childhood caries.BMC oral health · 2021Article
- Dental Caries and Associated Factors in 3-5-Year-Old Children in Guizhou Province, China: An Epidemiological Survey (2015-2016).Frontiers in public health · 2021Article
- Early Childhood Caries in 4- to 5-Year-Old Children in Erzurum, Turkey.Frontiers in public health · 2021Article
- Oral health behaviour, attitude towards, and knowledge of dental caries among mothers of 0- to 3-year-old children living in Kaunas, Lithuania.Clinical and experimental dental research · 2020Observational
- Identification of Non- Streptococcus mutans Bacteria from Predente Infant Saliva Grown on Mitis-Salivarius-Bacitracin Agar.The Journal of clinical pediatric dentistry · 2020Article
- Risk Factors of Dental Caries in the Thai Population: The Retrospective Cohort Study.Journal of International Society of Preventive & Community DentistryArticle
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEarly childhood caries (ECC) was a serious oral health concern with high prevalence and a low treatment rate in China, and few researches have focused on preschool children. This study aimed to explore the risk factors of ECC in Beijing, China.
methodsTotle of 712 children (mean age: 46.37 ± 5.44 months) participated in this prospective cohort study. Questionnaires and the levels of mutans streptococci in dental plaques and non-stimulated saliva, assessed using Dentocult SM strips, were collected at baseline, respectively. Two calibrated examiners checked for dental caries according to the WHO 1997 criteria at baseline and 1-year follow-up. Negative binomial regression was used for multivariate analysis of factors related to caries development.
resultsFor caries-free children at baseline, only plaque mutans streptococci (PMS) levels were associated with caries development (odds ratio [OR] = 1.68, 95% confidence interval [CI]: 1.08-2.61, P = 0.02). Children with high PMS levels (scored 2 and 3) had higher caries incidence (46.2% vs. 33.8%) and more caries increment (1.87 ± 3.17 vs. 0.90 ± 1.89) than those with low levels (scored 0 and 1). Among all participants, PMS (OR = 1.69, 95% CI: 1.32-2.23, P < 0.001) and previous caries experience (OR = 2.80, 95% CI: 2.20-3.56, P < 0.001) were related to caries increment.
conclusionsFor caries-free children, the only significant risk factor for ECC was high PMS levels. For all participants, besides high PMS levels, previous caries experience was another significant risk factor for caries development.
trial registrationThe study design, protocol, and informed consent forms were undertaken with the understanding of Declaration of Helsinki and were approved by the Human Research Ethics Committee of the School of Stomatology, Peking University, China (PKUSSIRB-2012042).
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