ReviewBMC biology2019
Circadian oscillator proteins across the kingdoms of life: structural aspects.
Review in BMC biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 91 citations in OpenAlex.
- Time-of-day-dependent effects of exercise on the hepatic clock and proteome in high-fat diet-fed mice.Journal of physiology and biochemistry · 2026Article
- Interplay between circadian and other transcription factors-Implications for cycling transcriptome reprogramming.FEBS letters · 2026Review
- Hydantion indolinones as AANAT inhibitors.Bioorganic & medicinal chemistry letters · 2026Article
- Flexible modulation of hybrid feedback loops in competitive biological oscillators.NPJ systems biology and applications · 2025Article
- A tool for modeling gene regulatory networks (GRN_modeler) and its applications to synthetic biology.Molecular systems biology · 2025Article
- TOC1 phosphorylation disproportionally enhances chromatin binding at rhythmic gene promoters.Science advances · 2025Article
- Diel Bacterioplankton Community Dynamics Under Contrasting Light Regimes.Environmental microbiology reports · 2025Article
- Seasonal timing and interindividual differences in shiftwork adaptation.NPJ digital medicine · 2025Article
- Clinical Chronobiology: Circadian Rhythms in Health and Disease.Seminars in neurology · 2025Review
- Sex-specific expression of circadian rhythms enables allochronic speciation.Evolution letters · 2025Article
- Article
- From resonance to chaos by modulating spatiotemporal patterns through a synthetic optogenetic oscillator.Nature communications · 2024Article
- A Knockout of the Photoreceptor PtAureo1a Results in Altered Diel Expression of Diatom Clock Components.Plants (Basel, Switzerland) · 2024Article
- Diel Cycle Proteomics: Illuminating Molecular Dynamics in Purple Bacteria for Optimized Biotechnological Applications.International journal of molecular sciences · 2024Article
- Article
- Unlocking allelic variation in circadian clock genes to develop environmentally robust and productive crops.Planta · 2024Review
- Genome-wide identification and characterization of flowering genes in Citrus sinensis (L.) Osbeck: a comparison among C. Medica L., C. Reticulata Blanco, C. Grandis (L.) Osbeck and C. Clementina.BMC genomic data · 2024Article
- Circadian regulation of MGMT expression and promoter methylation underlies daily rhythms in TMZ sensitivity in glioblastoma.Journal of neuro-oncology · 2024Article
- A novel small-animal locomotor activity recording device for biological clock research.Animal models and experimental medicine · 2024Article
- Fighting Against the Clock: Circadian Disruption and Parkinson's Disease.Journal of movement disorders · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Circadian oscillators are networks of biochemical feedback loops that generate 24-hour rhythms in organisms from bacteria to animals. These periodic rhythms result from a complex interplay among clock components that are specific to the organism, but share molecular mechanisms across kingdoms. A full understanding of these processes requires detailed knowledge, not only of the biochemical properties of clock proteins and their interactions, but also of the three-dimensional structure of clockwork components. Posttranslational modifications and protein-protein interactions have become a recent focus, in particular the complex interactions mediated by the phosphorylation of clock proteins and the formation of multimeric protein complexes that regulate clock genes at transcriptional and translational levels. This review covers the structural aspects of circadian oscillators, and serves as a primer for this exciting realm of structural biology.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.