Evidence map›Paper›PMID 30777042›Full record

ArticleBMC surgery2019

Hepatic hypertrophy and hemodynamics of portal venous flow after percutaneous transhepatic portal embolization.

Shingo Shimada, Toshiya Kamiyama, Hideki Yokoo, Tatsuya Orimo, Kenji Wakayama, Akihisa Nagatsu, Tatsuhiko Kakisaka, Hirofumi Kamachi, Daisuke Abo, Yusuke Sakuhara and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  3. Observational
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  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Shingo ShimadaDepartment of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Kita15-Nishi7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.
Toshiya KamiyamaDepartment of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Kita15-Nishi7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan. t-kamiya@med.hokudai.ac.jp.ORCID http://orcid.org/0000-0002-9157-7811
Hideki YokooDepartment of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Kita15-Nishi7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.
Tatsuya OrimoDepartment of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Kita15-Nishi7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.
Kenji WakayamaDepartment of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Kita15-Nishi7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.
Akihisa NagatsuDepartment of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Kita15-Nishi7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.
Tatsuhiko KakisakaDepartment of Surgery, Sapporo Kousei Hospital, Kita3-Higashi8, Chuo-Ku, Sapporo, Hokkaido, 060-0033, Japan.
Hirofumi KamachiDepartment of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Kita15-Nishi7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.
Daisuke AboDepartment of Radiology, Hokkaido University Graduate School of Medicine, Kita15-Nishi7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.
Yusuke SakuharaDepartment of Radiology, Hokkaido University Graduate School of Medicine, Kita15-Nishi7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.
Akinobu TaketomiDepartment of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Kita15-Nishi7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.
Hokkaido University · JPSendai Kousei Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPercutaneous transhepatic portal embolization (PTPE) is useful for safe major hepatectomy. This study investigated the correlation between hepatic hypertrophy and hemodynamics of portal venous flow by ultrasound sonography after PTPE.

methodsWe analyzed 58 patients with PTPE, excluding those who underwent recanalization (n = 10). Using CT volumetry results 2 weeks after PTPE, the patients were stratified into a considerable hypertrophy group (CH; n = 15) with an increase rate of remnant liver volume (IR-RLV) ≥ 40% and a minimal hypertrophy group (MH; n = 33) with an IR-RLV < 40%. We investigated the hemodynamics of portal venous flow after PTPE and the favorable factors for hepatic hypertrophy.

resultsUnivariate and multivariate analysis identified the indocyanine green retention rate at 15 min (ICGR15) and increase rate of portal venous flow volume (IR-pFV) at the non-embolized lobe on day 3 after PTPE as independent favorable factors of IR-RLV. Patients with IR-pFV on day 3 after PTPE ≥100% and ICGR15 ≤ 15% (n = 13) exhibited significantly increased IR-RLV compared with others (n = 35).

conclusionsCases with high IR-pFV on day 3 after PTPE exhibited better hepatic hypertrophy. Preserved liver function and increased portal venous flow on day 3 were important.

Indexed as

Embolization, TherapeuticLiverAgedFemaleGallbladder NeoplasmsHemodynamicsHepatectomyHumansHypertrophyLiver CirculationLiver NeoplasmsLiver RegenerationMaleMiddle AgedOrgan SizePortal VeinHepatic hypertrophyPercutaneous transhepatic portal embolizationPortal venous flow

Identifiers

PMID30777042
PMCPMC6379972
OpenAlexW2920823754

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.