Evidence map›Paper›PMID 30777027›Full record

Trial reportBMC anesthesiology2019

Ultrasound guided continuous Quadratus Lumborum block hastened recovery in patients undergoing open liver resection: a randomized controlled, open-label trial.

Qiang Zhu, Li Li, Zhaoyun Yang, Jinmei Shen, Rong Zhu, Yu Wen, Wenwu Cai, Lei Liu

Open access · goldAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.

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  5. Randomized Clinical Trial Comparing Quadratus Lumborum Block and Intrathecal Morphine for Postcesarean Analgesia.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Qiang ZhuDepartment of Anesthesiology, The Second Xiangya Hospital of Central South University, 139 Renmin Middle Road, Hunan, China.
Li LiDepartment of Anesthesiology, The Second Xiangya Hospital of Central South University, 139 Renmin Middle Road, Hunan, China.
Zhaoyun YangDepartment of Anesthesiology, The Second Xiangya Hospital of Central South University, 139 Renmin Middle Road, Hunan, China.
Jinmei ShenDepartment of Anesthesiology, The Second Xiangya Hospital of Central South University, 139 Renmin Middle Road, Hunan, China.
Rong ZhuDepartment of Anesthesiology, The Second Xiangya Hospital of Central South University, 139 Renmin Middle Road, Hunan, China.
Yu WenDepartment of Hepatobiliary Surgery, The Second Xiangya Hospital of Central South University, 139 Renmin Middle Road, Hunan, China.
Wenwu CaiDepartment of Hepatobiliary Surgery, The Second Xiangya Hospital of Central South University, 139 Renmin Middle Road, Hunan, China.
Lei LiuDepartment of Anesthesiology, The Second Xiangya Hospital of Central South University, 139 Renmin Middle Road, Hunan, China. liulei001@csu.edu.cn.ORCID 0000-0003-4558-4903
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundQuadratus lumborum (QL) block is increasingly being used as a new abdominal nerve block technique. In some studies of mid and lower abdominal and hip analgesia, continuous QL block achieved favorable outcomes as an alternative to continuous intravenous analgesia with opioids. However, the use of continuous QL block for upper abdominal pain is less well characterized. This study aimed to investigate the effects of continuous anterior QL block (CQLB) on postoperative pain and recovery in patients undergoing open liver resection.

methodsSixty-three patients underwent elective open liver resection were randomly divided into continuous anterior QL block (CQLB, n = 32) group and patient-controlled intravenous analgesia (PCIA, n = 31) group. Patients in CQLB group underwent ultrasound-guided anterior QL block at the second lumbar vertebral transverse processes before general anesthesia, followed by postoperative CQLB analgesia. Patients in PCIA group underwent continuous intravenous analgesia postoperatively. Postoperative numerical rating scale (NRS) pain scores upon coughing and at rest, self-administered analgesic counts, rate of rescue analgesic use, time to first out-of-bed activity and anal flatus after surgery, and incidences of analgesic-related adverse effects were recorded.

resultsPostoperative NRS pain scores on coughing in CQLB group at different time points and NRS pain score at rest 48 h after surgery were significantly lower than those in PCIA group (P < 0.05). Time to first out-of-bed activity and anal flatus after surgery in CQLB group were significantly earlier than those in PCIA group (P < 0.05). No significant differences of postoperative self-administered analgesic counts, rate of postoperative rescue analgesic usage, or incidences of analgesic-related adverse effects were found between the two groups (P > 0.05).

conclusionsUltrasound-guided anterior QL block significantly alleviated the pain during coughing after surgery, shortened the time to first out-of-bed activity and anal flatus, promoting postoperative recovery of the patients undergoing open liver resection.

trial registrationThis study has been registered in April 1, 2018 on Chinese Clinical Trail Registry, the registration number is ChiCTR1800015454 .

Indexed as

AdultAnalgesia, Patient-ControlledAnalgesicsFemaleHepatectomyHumansMaleMiddle AgedNerve BlockPilot ProjectsPostoperative PainUltrasonography, InterventionalAnalgesicsContinuous quadratus lumborum blockLiver resectionPostoperative analgesiaUltrasound guidance

Identifiers

PMID30777027
PMCPMC6380018
OpenAlexW2922231446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.