Evidence map›Paper›PMID 30775692›Full record

ArticleJournal of engineering and science in medical diagnostics and therapy2018

A 3D-Printed Patient-Specific Phantom for External Beam Radiation Therapy of Prostate Cancer.

Christopher L Lee, Max C Dietrich, Uma G Desai, Ankur Das, Suhong Yu, Hong F Xiang, C Carl Jaffe, Ariel E Hirsch, B Nicolas Bloch

Abstract read
In one paragraph

Article in Journal of engineering and science in medical diagnostics and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Christopher L LeeFranklin W. Olin College of Engineering, 1000 Olin Way, Needham MA 02492.
Max C DietrichFranklin W. Olin College of Engineering, 1000 Olin Way, Needham MA 02492.
Uma G DesaiFranklin W. Olin College of Engineering, 1000 Olin Way, Needham MA 02492.
Ankur DasFranklin W. Olin College of Engineering, 1000 Olin Way, Needham MA 02492.
Suhong YuDepartment of Radiology Oncology, Boston Medical Center & Boston University School of Medicine, 820 Harrison Ave., Boston, MA 02118.
Hong F XiangDepartment of Radiology Oncology, Boston Medical Center & Boston University School of Medicine, 820 Harrison Ave., Boston, MA 02118.
C Carl JaffeDepartment of Radiology, Boston Medical Center & Boston University School of Medicine, 820 Harrison Ave., Boston, MA 02118.
Ariel E HirschDepartment of Radiology Oncology, Boston Medical Center & Boston University School of Medicine, 820 Harrison Ave., Boston, MA 02118.
B Nicolas BlochDepartment of Radiology, Boston Medical Center & Boston University School of Medicine, 820 Harrison Ave., Boston, MA 02118.
Boston University · USFranklin W. Olin College of Engineering · USBoston Medical Center · US

Funding

NASA NNX10AT92H
6 · The paper itself

Abstract

This paper presents the design evolution, fabrication, and testing of a novel patient and organ-specific, 3D printed phantom for external beam radiation therapy of prostate cancer. In contrast to those found in current practice, this phantom can be used to plan and validate treatment tailored to an individual patient. It contains a model of the prostate gland with a dominant intraprostatic lesion, seminal vesicles, urethra, ejaculatory duct, neurovascular bundles, rectal wall, and penile bulb generated from a series of combined T2-weighted/dynamic contrast-enhanced magnetic resonance images. The iterative process for designing the phantom based on user interaction and evaluation is described. Using the CyberKnife System at Boston Medical Center a treatment plan was successfully created and delivered. Dosage delivery results were validated through gamma index calculations based on radiochromic film measurements which yielded a 99.8% passing rate. This phantom is a demonstration of a methodology for incorporating high-contrast magnetic resonance imaging into computed-tomography-based radiotherapy treatment planning; moreover, it can be used to perform quality assurance.

Identifiers

PMID30775692
PMCPMC6376205
OpenAlexW2876137970

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.