ArticleInternational journal of reproductive biomedicine2018
Cyclophosphamide-induced testicular toxicity ameliorate by
Article in International journal of reproductive biomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 21 citations in OpenAlex.
- Yam-Active Protein Protects Against Cyclophosphamide-Induced Testicular Injury by Suppressing Inflammatory Responses.Molecules (Basel, Switzerland) · 2026Article
- Saroglitazar Mitigated Cyclophosphamide-Induced Testicular Injury: Crosstalk Between Oxidative Stress, Inflammation and Apoptosis.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Cyclophosphamide-induced testicular injury: the role of chrysin in mitigating iron overload and ferroptosis.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Food and medicine homology: a potential nutritional intervention strategy for post-acute COVID-19 syndrome.Frontiers in pharmacology · 2025Review
- Alkylating agents-induced gonadotoxicity in prepubertal males: Insights on the clinical and preclinical front.Clinical and translational science · 2024Review
- Preventive effects of quercetin against inflammation and apoptosis in cyclophosphamide-induced testicular damage.Iranian journal of basic medical sciences · 2024Article
- Therapeutic potential of bone marrow mesenchymal stem cells in cyclophosphamide-induced infertility.Frontiers in pharmacology · 2023Article
- Protective effects of chlorogenic acid against ionizing radiation-induced testicular toxicity.Heliyon · 2022Article
- Preventive and therapeutic effects ofAvicenna journal of phytomedicineArticle
- Protective effects of hydroalcoholic extract ofAvicenna journal of phytomedicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCyclophosphamide (CP) is one of the most invasive chemotherapeutic agents, which used commonly despite of its wide spectrum toxicity. Clinical evidence showed toxic side effects of CP in multiple organ systems.
objectiveThe objective of the present study was to evaluate the effects of MATERIALS AND
methodsAdult male Wistar rats (220±30 gr) were randomly divided into four groups (n=7 in each). Group 1 as control received normal saline by gavage, group 2 received CP (6.1 mg/kg/day, i.p.) for a period of 50 days. Group 3 received
resultsSerum testosterone concentration was significantly decreased whereas the level of malondialdehyde and DNA damage were significantly increased in animals of CP group (p<0.01). Co-administration of
conclusionThe findings confirmed the protective effects of
Indexed as
Identifiers
30775687PMC6350852W2911289037What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.