Evidence map›Paper›PMID 30775644›Full record

ArticleACS omega2019

Evidence for Hidden Involvement of N3-Protonated Guanine in RNA Structure and Function.

Antarip Halder, Saurabh Vemuri, Rohit Roy, Jayanth Katuri, Dhananjay Bhattacharyya, Abhijit Mitra

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. The Role of Proton Transfer on Mutations.Frontiers in chemistry · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Antarip HalderCenter for Computational Natural Sciences and Bioinformatics (CCNSB), International Institute of Information Technology, Hyderabad (IIIT-H), Gachibowli, Hyderabad 500032, Telangana, India.
Saurabh VemuriCenter for Computational Natural Sciences and Bioinformatics (CCNSB), International Institute of Information Technology, Hyderabad (IIIT-H), Gachibowli, Hyderabad 500032, Telangana, India.
Rohit RoyCenter for Computational Natural Sciences and Bioinformatics (CCNSB), International Institute of Information Technology, Hyderabad (IIIT-H), Gachibowli, Hyderabad 500032, Telangana, India.
Jayanth KaturiCenter for Computational Natural Sciences and Bioinformatics (CCNSB), International Institute of Information Technology, Hyderabad (IIIT-H), Gachibowli, Hyderabad 500032, Telangana, India.
Dhananjay BhattacharyyaComputational Science Division, Saha Institute of Nuclear Physics (SINP), 1/AF, Bidhannagar, Kolkata 700064, India.
Abhijit MitraCenter for Computational Natural Sciences and Bioinformatics (CCNSB), International Institute of Information Technology, Hyderabad (IIIT-H), Gachibowli, Hyderabad 500032, Telangana, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Charged nucleobases have been found to occur in several known RNA molecules and are considered essential for their structure and function. The mechanism of their involvement is however not yet fully understood. Revelation of the role of N7-protonated guanine, in modulating the geometry and stability of noncanonical base pairs formed through its unprotonated edges [Watson-Crick (WC) and sugar], has triggered the need to evaluate the feasibility of similar roles of other protonated nucleobases [Halder et al.,

Identifiers

PMID30775644
PMCPMC6372247

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.