Evidence map›Paper›PMID 30775639›Full record

ArticleHardwareX2018

An inexpensive modified weight-bearing device assembled in-house for high throughput unbiased behavioral pain assessment in mice.

Brendan Drackley, Matt Holtz, Jay Yang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in HardwareX, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Brendan DrackleyDepartment of Anesthesiology, University of Wisconsin School of Medicine and Public Health Madison, WI, USA.
Matt HoltzDepartment of Anesthesiology, University of Wisconsin School of Medicine and Public Health Madison, WI, USA.
Jay YangDepartment of Anesthesiology, University of Wisconsin School of Medicine and Public Health Madison, WI, USA.
University of Wisconsin–Madison · US

Funding

Treatment for neuropathic pain targeting selective inhibition of MEKR01GM105665 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI YANG, JAY · 2014 to 2017
$1.1M
Sigma 1 receptor as a master regulator of pronociceptive protein trafficking in tR01GM107054 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI RUOHO, ARNOLD EINO, YANG, JAY · 2013 to 2016
$1.1M
NIGMS NIH HHS R01 GM105665NIGMS NIH HHS R01 GM107054
6 · The paper itself

Abstract

Assessment of pain in rodents is essential for analgesic development and investigations of fundamental neurobiology of pain. We have previously reported on a modified weight bearing apparatus we call VASIC (voluntarily accessed static incapacitance chamber) enabling unbiased and high throughput assessment of pain in rats. The present report provides a detailed description of the construction of the apparatus with all necessary computer assisted design files for the printed circuit board and the plastic components, and the required software for controlling the data capture and data analysis hosted in an online source file repository to allow assembly of the device in-house at a cost affordable to most academic laboratories. We extend the application of the apparatus to assess weight bearing in mice to enable the use of genetic mice models to study pain.

Indexed as

Arduino shieldMus musculusPain assessmentWeight bearing

Identifiers

PMID30775639
PMCPMC6375313
OpenAlexW2804787263

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.