ArticleArchives of medical sciences. Atherosclerotic diseases2018
The "cholesterol paradox" among inpatients - retrospective analysis of medical documentation.
Article in Archives of medical sciences. Atherosclerotic diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
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- The Cholesterol Paradox in Long-Livers from a Sardinia Longevity Hot Spot (Blue Zone).Nutrients · 2025Article
- Association of vitamin D receptor gene polymorphisms with rheumatoid arthritis.Archives of medical science : AMS · 2024Article
- Epidemiology of multiple myeloma in Poland in the years 2008-2017.Archives of medical science : AMS · 2023Article
- Article
- Nutritional Impact of Percutaneous Endoscopic Gastrostomy: A Retrospective Single-center Study.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2022Article
- Very Low-Carbohydrate High-Fat Diet Improves Risk Markers for Cardiometabolic Health More Than Exercise in Men and Women With Overfat Constitution: Secondary Analysis of a Randomized Controlled Clinical Trial.Frontiers in nutrition · 2022Article
- The Association between Diabetes Mellitus and Keratoplasty in Poland in the Years 2013-2017.International journal of environmental research and public health · 2021Article
- Retrospective cohort study of patients qualified for lung transplantation due to idiopathic pulmonary fibrosis - single-centre experience.Archives of medical science : AMS · 2020Article
- Usefulness of mean platelet volume to platelet count ratio for predicting the risk of mortality in community-acquired pneumonia.Archives of medical science : AMS · 2020Article
- Homogeneous Group approach to Elixhauser comorbidity for hospital death using administrative data.Archives of medical science : AMS · 2020Article
- Takotsubo syndrome - fatal prognosis of patients with low body mass index in 5-year follow-up.Archives of medical science : AMS · 2020Article
- Intrahospital critical patient transport from the emergency department.Archives of medical science : AMS · 2020Article
- Should we admit more patients not requiring invasive ventilation to reduce excess mortality in Polish intensive care units? Data from the Silesian ICU Registry.Archives of medical science : AMS · 2019Article
- Does stress hyperglycemia affect mortality? Acute myocardial infarction - case control study.Archives of medical sciences. Atherosclerotic diseases · 2019Article
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7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThere is evidence of positive relationships between cholesterol concentration and risk of cardiovascular diseases. However, higher mortality in patients with a low cholesterol level has been reported (the "cholesterol paradox"). MATERIAL AND
methodsMedical records of 34 191 inpatients between 2014 and 2016 were reviewed and the relationships between total (TC), low-density lipoprotein (LDL-C) and high-density lipoprotein (HDL-C) cholesterol and triglyceride blood concentrations and all-cause in-hospital death and readmission within 14 and 30 days and 1 year were determined in univariate and multivariate analyses.
resultsPatients with TC in the lower quartile and LDL-C < 70 mg/dl had greater risk of the outcomes measured than individuals with a TC level in the remaining quartiles and LDL-C ≥ 70 mg/dl. Moreover, patients with TC in the highest quartile, OR (95% CI): 0.36 (0.13-0.99),
conclusionsA significant effect of a "cholesterol paradox" linking better prognosis with higher blood lipid concentration was found only in univariate analysis but, after adjustment for clinical characteristics in multivariate analysis, the plasma lipid level had a neutral influence on the occurrence of the measured outcomes. This suggests that a low cholesterol level should be interpreted as a biomarker of illness severity.
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