ReviewOsteoporosis and sarcopenia2018
School-based exercise interventions effectively increase bone mineralization in children and adolescents.
Review in Osteoporosis and sarcopenia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 29 citations in OpenAlex.
- Skeletal Effects of Nine Months of Physical Activity in Obese and Healthy Weight Children.Medicine and science in sports and exercise · 2020Trial
- Mechanical Stimulation Drives Multicellular Synergy and Signaling Pathways in Developing Skeletal Tissues.Sports medicine (Auckland, N.Z.) · 2026Review
- The Crucial Role of Exercise in Promoting Adolescent Bone Health.Advances in experimental medicine and biology · 2026Review
- Beyond Weight Loss: Optimizing GLP-1 Receptor Agonist Use in Children.Children (Basel, Switzerland) · 2025Review
- The Era of Resistance Training as a Primary Form of Physical Activity for Physical Fitness and Health in Youth Has Come.Sports medicine (Auckland, N.Z.) · 2025Review
- Biomechanics of a Drop Landing: Osteogenic Stimulus Measures May Vary.Journal of musculoskeletal & neuronal interactions · 2025Article
- Article
- Peak Bone Mass Formation: Modern View of the Problem.Biomedicines · 2023Review
- Unintended consequences of glucagon-like peptide-1 receptor agonists medications in children and adolescents: A call to action.Journal of clinical and translational science · 2023Article
- The inverse relationship between fatness and bone mineral content is mediated by the adolescent appendicular skeletal muscle mass index: The Cogni-Action Project.Frontiers in nutrition · 2022Article
- The effect of physical activity intervention and nutritional habits on anthropometric measures in elementary school children: the health oriented pedagogical project (HOPP).International journal of obesity (2005) · 2021Article
- Influence of Mediterranean Diet Adherence and Physical Activity on Bone Health in Celiac Children on a Gluten-Free Diet.Nutrients · 2021Article
- School-based nutrition interventions can improve bone health in children and adolescents.Osteoporosis and sarcopenia · 2021Review
- Response of Bone Metabolism Markers to Ice Swimming in Regular Practitioners.Frontiers in physiology · 2021Article
- The Impact of Diet and Physical Activity on Bone Health in Children and Adolescents.Frontiers in endocrinology · 2021Review
- Exercise and Peak Bone Mass.Current osteoporosis reports · 2020Review
- Cross-sectional and longitudinal associations between physical activity, sedentary behaviour and bone stiffness index across weight status in European children and adolescents.The international journal of behavioral nutrition and physical activity · 2020Article
- How Physical Activity across the Lifespan Can Reduce the Impact of Bone Ageing: A Literature Review.International journal of environmental research and public health · 2020Review
- [Fractures and bone mineral density in childhood].Zeitschrift fur Rheumatologie · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoporosis and fragility fractures have become major global public health concerns, and they can be prevented by maximizing peak bone mass during childhood and adolescence with weight-bearing physical activity, which can result in stronger and healthier bones that significantly decrease the risk of osteoporosis and fragility fractures in adulthood and the elderly years. From a public health perspective, implementing weight-bearing physical activity for children and adolescents is best achieved with school-based exercise interventions, and a review of school-based exercise interventions was conducted to determine their effectiveness in increasing bone mineral density (BMD) and/or bone mineral content (BMC). Seventeen studies were reviewed, all school-based exercise interventions utilized jumping exercises, and 15 of the 17 studies found at least one significant increase in measures of BMD and/or BMC for the total body, and/or at the hip, vertebrae, and/or wrist. One study that found no significant differences did report significant increases in bone structural strength, and the other study with no significant differences had exercises that measured and reported the lowest ground reaction forces (GRFs) of only 2-3 times body weight (BW), whereas the other studies that showed significant increase(s) in BMD and/or BMC had exercise with measured and reported GRFs ranging from 3.5 × to 8.8 × BW. School-based exercise interventions are time- and cost-efficient and effective in increasing BMD and/or BMC in children and adolescents, but must incorporate high-intensity exercise, such as high-impact jumping of sufficient GRFs, in order to significantly increase bone mineralization for osteoporosis and fragility fracture prevention later in life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.