Evidence map›Paper›PMID 30775521›Full record

ArticleOsteoporosis and sarcopenia2017

Relationship between coronary atherosclerosis in coronary computed tomography angiography and serum vitamin D level.

Ah-Young Lee, Jin-Kyu Kim, Jee-Hyun Kang, Byung-Yeon Yu, Seong-Ju Kim

Abstract read
In one paragraph

Article in Osteoporosis and sarcopenia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Novel Insights into the Molecular Mechanisms of Atherosclerosis.International journal of molecular sciences · 2023
    Review
  3. Review
  4. Review
  5. Vitamin D and coronary atherosclerosis.Osteoporosis and sarcopenia · 2017
    Article
  6. Reply on "Vitamin D and coronary atherosclerosis".Osteoporosis and sarcopenia · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ah-Young LeeDepartment of Family Medicine, Konyang University Hospital, Daejeon, South Korea.
Jin-Kyu KimDepartment of Family Medicine, Konyang University Hospital, Daejeon, South Korea.
Jee-Hyun KangDepartment of Family Medicine, Konyang University Hospital, Daejeon, South Korea.
Byung-Yeon YuDepartment of Family Medicine, Konyang University Hospital, Daejeon, South Korea.
Seong-Ju KimDepartment of Family Medicine, Konyang University Hospital, Daejeon, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesVitamin D deficiency has been shown to influence the development of some cardiovascular disease. In this study, the association between the existence of coronary artery plaque and vitamin D was examined among participants who were not previously diagnosed with coronary artery disease.

methodsA total of 339 participants (246 men and 93 women) who visited a health examination center for check-up including blood test for serum vitamin D level and coronary computed tomography angiography (CCTA) were selected for this study.

resultsAmong the total 339 participants, 106 displayed coronary artery plaques. The serum 25-hydroxy vitamin D (25(OH)D) level of the group with plaque was lower than that of the group without (17.7 ± 7.72 ng/mL vs. 19.6 ± 7.12 ng/mL, P = 0.0316). The group with plaque had higher incidence rates of diabetes mellitus, hypertension, and dyslipidemia than that without (P = 0.0078, P = 0.0065, and P = 0.0174, respectively). The former displayed higher serum glucose and glycated hemoglobin levels than the latter (P = 0.0055 and P = 0.0137, respectively). The group with plaque showed higher systolic and diastolic blood pressure than that without (P < 0.0001 and P = 0.0012, respectively). Stepwise multivariate logistic regression analysis revealed that 25(OH)D (coefficient, -0.06; odd ratio, 0.9433; 95% confidence interval, 0.8967-0.9924), age, and sex were independently related with presence of coronary artery plaque.

conclusionsRelatively low vitamin D level was observed among participants with plaque, which was determined through CCTA during a health examination. Plaque formation and serum 25(OH)D level showed inverse relationship.

Indexed as

Coronary CT angiographyVitamin D

Identifiers

PMID30775521
PMCPMC6372824

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.