Evidence map›Paper›PMID 30775382›Full record

ArticleBioMed research international2019

Planning, Implementing, and Running a Multicentre Preterm Birth Study with Biobank Resources in Brazil: The Preterm SAMBA Study.

Renato T Souza, Jose G Cecatti, Maria L Costa, Jussara Mayrink, Rodolfo C Pacagnella, Renato Passini, Kleber G Franchini, Francisco E Feitosa, Iracema M Calderon, Edilberto A Rocha Filho and 5 more

Abstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Thinking on the purposes, roles and activities of networks for research on maternal and perinatal health: opinions of coordinators and members.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Renato T SouzaDepartment of Obstetrics and Gynecology, University of Campinas (UNICAMP), School of Medical Sciences, Campinas, SP, Brazil.ORCID 0000-0002-9075-9269
Jose G CecattiDepartment of Obstetrics and Gynecology, University of Campinas (UNICAMP), School of Medical Sciences, Campinas, SP, Brazil.ORCID 0000-0003-1285-8445
Maria L CostaDepartment of Obstetrics and Gynecology, University of Campinas (UNICAMP), School of Medical Sciences, Campinas, SP, Brazil.
Jussara MayrinkDepartment of Obstetrics and Gynecology, University of Campinas (UNICAMP), School of Medical Sciences, Campinas, SP, Brazil.ORCID 0000-0001-5957-4365
Rodolfo C PacagnellaDepartment of Obstetrics and Gynecology, University of Campinas (UNICAMP), School of Medical Sciences, Campinas, SP, Brazil.ORCID 0000-0002-5739-0009
Renato PassiniDepartment of Obstetrics and Gynecology, University of Campinas (UNICAMP), School of Medical Sciences, Campinas, SP, Brazil.ORCID 0000-0001-8247-4549
Kleber G FranchiniLNBio-Brazilian National Laboratory of Biosciences and University of Campinas (UNICAMP) School of Medical Sciences, University of Campinas (UNICAMP), Campinas, SP, Brazil.
Francisco E FeitosaMEAC-Maternity School of The Federal University of Ceará, Fortaleza, CE, Brazil.ORCID 0000-0002-7583-2974
Iracema M CalderonDepartment of Obstetrics and Gynecology, Botucatu Medical School, Sao Paulo State University-Unesp, Botucatu, Brazil.
Edilberto A Rocha FilhoDepartment of Maternal and Child Health, Maternity of The Clinics Hospital, Federal University of Pernambuco, Recife, PE, Brazil.ORCID 0000-0002-6434-2654
Débora F LeiteDepartment of Maternal and Child Health, Maternity of The Clinics Hospital, Federal University of Pernambuco, Recife, PE, Brazil.
Janete VettorazziDepartment of Obstetrics and Gynecology, Maternity of The Clinics Hospital, Federal University of RS, Porto Alegre, RS, Brazil.
Louise C KennyIrish Centre for Fetal and Neonatal Translational Research (INFANT), Department of Obstetrics and Gynaecology, University College Cork, Cork, Ireland.
Philip N BakerCollege of Medicine, Biological Sciences and Psychology, University of Leicester, Leicester, UK.
The Preterm Samba Study GroupDepartment of Obstetrics and Gynecology, University of Campinas (UNICAMP), School of Medical Sciences, Campinas, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur aim was to describe the steps in planning, implementing, and running a multicentre cohort study of maternal and perinatal health using a high-quality biobank comprised of maternal serum, plasma, and hair samples collected from five sites in Brazil. The Preterm SAMBA study, conducted by the Brazilian Network for Studies on Reproductive and Perinatal Health, was an innovative approach used to identify women at higher risk for preterm birth. It is also of great importance in the study of other maternal and perinatal complications in the context of Brazil, which is a middle-income country.

methodsWe described phases of planning, implementing, and running the Preterm SAMBA study, a multicentre Brazilian cohort study of low-risk nulliparous pregnant women, to validate a set of metabolite biomarkers for preterm birth identified in an external cohort. Procedures and strategies used to plan, implement, and maintain this multicentre preterm birth study are described in detail. Barriers and experience cited in the current narrative are not usually discussed in the scientific literature or published study protocols.

resultsSeveral barriers and strategies were identified in different phases of the Preterm SAMBA study at different levels of the study framework (steering committee; coordinating and local centres). Strategies implemented and resources used in the study are a legacy of the Brazilian Network, aimed at training collaborators in such complex settings.

conclusionThe Brazilian Network for Studies on Reproductive and Perinatal Health has gained some experience in conducting a multicentre cohort study using a resourceful biobank which may be helpful to other research groups and maternal/perinatal health networks that plan on employing a similar approach to a similar background.

Indexed as

Biological Specimen BanksAdultBrazilFemaleHumansInfant, NewbornMaternal HealthPregnancyPremature BirthReproductionRisk Factors

Identifiers

PMID30775382
PMCPMC6354138

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.